{"id":1653,"date":"2021-02-04T05:12:43","date_gmt":"2021-02-03T21:12:43","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1653"},"modified":"2021-02-04T05:12:43","modified_gmt":"2021-02-03T21:12:43","slug":"the-origin-of-a-common-compound-about-121507-34-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1653","title":{"rendered":"The origin of a common compound about 121507-34-4"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 121507-34-4, name is 5-Isopropoxy-1H-pyrazol-3-amine, A new synthetic method of this compound is introduced below., Application In Synthesis of 5-Isopropoxy-1H-pyrazol-3-amine<\/a><\/p>\n

5-bromo-N’-(5-isopropoxy-1H-pyrazol-3-yl)-N-[(3-methylisoxazol-5-yl)methyl]pyrimidine-2,4-diamine (also known as 5-bromo-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-N’-(5-propan-2-yloxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine), used as starting material, was prepared as follows: a) To a solution of 5-isopropoxy-1H-pyrazol-3-amine (2.0 g, 14.2 mmol) in dry tetrahydrofuran (60 ml) under a nitrogen atmosphere was added triethylamine and the mixture cooled to 0 C. A solution of 5-bromo-2,4-dichloropyrimidine (3.23 g, 14.2 mmol) in dry tetrahydrofuran (30 ml) was added dropwise and the mixture was allowed to stir at room temperature for 18 hours. The mixture was evaporated and the residue crystallised with ethyl acetate. The mixture was filtered and the residue triturated thoroughly with water. The resultant solid was filtered and then left to dry overnight to give 5-bromo-2-chloro-N-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidin-4-amine (1.645 g, 35% yield). MS: m\/z 332 (MH+).<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[346,131],"tags":[126],"class_list":["post-1653","post","type-post","status-publish","format-standard","hentry","category-121507-34-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe origin of a common compound about 121507-34-4<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 121507-34-4, name is 5-Isopropoxy-1H-pyrazol-3-amine, A new synthetic method of this compound is introduced below., Application In Synthesis of 5-Isopropoxy-1H-pyrazol-3-amine\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1653\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The origin of a common compound about 121507-34-4\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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