{"id":1642,"date":"2021-02-03T05:01:30","date_gmt":"2021-02-02T21:01:30","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1642"},"modified":"2021-02-03T05:01:30","modified_gmt":"2021-02-02T21:01:30","slug":"the-important-role-of-13788-84-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1642","title":{"rendered":"The important role of 13788-84-6"},"content":{"rendered":"

Related Products of 13788-84-6<\/a>, These common heterocyclic compound, 13788-84-6, name is 3-Methyl-4-phenyl-1H-pyrazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.<\/p>\n

In a nitrogen-purged glove box, (oxybis(2,1-phenylene))bis(diphenylphosphine) (1.0 g, 1.85 mmol) and toluene (30 mL) were added to a glass jar, equipped with a PTFE-coated stir bar. While stirring, mesitylcopper(I) (0.31 g, 1.70 mmol) was added. After a few minutes, 3-methyl-4-phenyl-1H-pyrazole (0.30 g, 1.90) was added, and the resulting mixture was heated at 90C for 3 hours. The mixture was then cooled to 60C, and stirred overnight. After cooling to room temperature, the solid that had formed was collected by filtration. The isolated solid was rinsed with toluene, followed by hexanes, and dried at 70C, under vacuum, to afford the title compound (0.66 g). Crystals were grown by slow evaporation of dichloromethane, and characterized by single crystal X-Ray crystallography, supporting the above molecular structure.<\/p>\n

The synthetic route of 13788-84-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 13788-84-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[342,131],"tags":[126],"class_list":["post-1642","post","type-post","status-publish","format-standard","hentry","category-13788-84-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 13788-84-6<\/title>\n<meta name=\"description\" content=\"Related Products of 13788-84-6, These common heterocyclic compound, 13788-84-6, name is 3-Methyl-4-phenyl-1H-pyrazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of 13788-84-6\" \/>\n<meta property=\"og:description\" content=\"Related Products of 13788-84-6, These common heterocyclic compound, 13788-84-6, name is 3-Methyl-4-phenyl-1H-pyrazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-02T21:01:30+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642\",\"name\":\"The important role of 13788-84-6\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-02-02T21:01:30+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 13788-84-6, These common heterocyclic compound, 13788-84-6, name is 3-Methyl-4-phenyl-1H-pyrazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1642#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The important role of 13788-84-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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