{"id":1616,"date":"2021-02-01T04:55:23","date_gmt":"2021-01-31T20:55:23","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1616"},"modified":"2021-02-01T04:55:23","modified_gmt":"2021-01-31T20:55:23","slug":"new-learning-discoveries-about-5775-82-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1616","title":{"rendered":"New learning discoveries about 5775-82-6"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5775-82-6, name is 4-Bromo-1,3-dimethyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 4-Bromo-1,3-dimethyl-1H-pyrazole<\/a><\/p>\n

Into a dry flask under N2 is added dry diethyl ether (150 mL) and 1 ,3-dimethyl-4- bromopyrazole (5g, 28.6 mmol, Combi-Blocks). The mixture is cooled to -78C in a dry ice\/acetone bath. To this solution is added f-BuLi (37 mL, 62.9 mmol, 1.7 M in pentane) over 5 min, which is allowed to stir for 30 min at -78 C. 2-isopropoxy-4,4,5,5- tetramethyl-1 ,3,2-dioxaborolane (6.4 mL, 31.4 mmol) is added in one portion via syringe. Stirring is continued at -78 C for 15 min. The reaction mixture is allowed to warm to RT and is then stirred for 30 min. The reaction mixture is poured into saturated NH4CI, then extracted with EtOAc (3x). The combined organic layers are dried (Na2S04), filtered and evaporated under reduced pressure. The residue is dissolved in hexanes (6 mL). The solvent is evaporated under reduced pressure and then dried under high vacuum for 48 h to provide boronate ester 24a.<\/p>\n

According to the analysis of related databases, 5775-82-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 5775-82-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[337,131],"tags":[126],"class_list":["post-1616","post","type-post","status-publish","format-standard","hentry","category-5775-82-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about 5775-82-6<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5775-82-6, name is 4-Bromo-1,3-dimethyl-1H-pyrazole, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New learning discoveries about 5775-82-6","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5775-82-6, name is 4-Bromo-1,3-dimethyl-1H-pyrazole, This compound has unique chemical properties. 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