{"id":1606,"date":"2021-01-29T04:46:54","date_gmt":"2021-01-28T20:46:54","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1606"},"modified":"2021-01-29T04:46:54","modified_gmt":"2021-01-28T20:46:54","slug":"research-on-new-synthetic-routes-about-473528-88-0","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1606","title":{"rendered":"Research on new synthetic routes about 473528-88-0"},"content":{"rendered":"

Reference of 473528-88-0<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 473528-88-0, name is 4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

4-Bromo-2-methyl-2H-pyrazole-3-carbaldehyde (1.00 g; 5.29 mmol) is dissolved in 5.0 ml of anhydrous THF and cooled down to -78 C. Phenylmagnesium chloride 2 mol\/l (6.61 ml; 13.2 mmol) is added and the reaction mixture is stirred for 1 hour. It is warmed up to 0 C. and is quenched carefully with water, then extracted with DCM. The organic layers are pooled, dried over MgSO4 and purified by using reversed phase chromatography under basic conditions. Yield: 82% (1.16 g; 4.35 mmol);HPLC-MS: (M+H)+= 267; tRet=1.59 min; method FECBM3ESI.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[335,131],"tags":[126],"class_list":["post-1606","post","type-post","status-publish","format-standard","hentry","category-473528-88-0","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nResearch on new synthetic routes about 473528-88-0<\/title>\n<meta name=\"description\" content=\"Reference of 473528-88-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 473528-88-0, name is 4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1606\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on new synthetic routes about 473528-88-0\" \/>\n<meta property=\"og:description\" content=\"Reference of 473528-88-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 473528-88-0, name is 4-Bromo-1-methyl-1H-pyrazole-5-carbaldehyde belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1606\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-28T20:46:54+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1606\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1606\",\"name\":\"Research on new synthetic routes about 473528-88-0\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-01-28T20:46:54+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Reference of 473528-88-0, In the next few decades, the world population will flourish. 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