{"id":1596,"date":"2021-01-28T04:44:53","date_gmt":"2021-01-27T20:44:53","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1596"},"modified":"2021-01-28T04:44:53","modified_gmt":"2021-01-27T20:44:53","slug":"discovery-of-20154-03-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1596","title":{"rendered":"Discovery of 20154-03-4"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 20154-03-4, name is 3-(Trifluoromethyl)-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 20154-03-4, Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole<\/a><\/p>\n

Reference Production Example 12-1 4-bromo-3-(trifluoromethyl)-1H-pyrazole 3.50 g of 3-(trifluoromethyl)-1H-pyrazole was suspended in 45 ml of water, and 3.2 g of 50 % aqueous solution of sodium hydroxide was added to it. The mixture was cooled to 0 C, and then 3.20 g of bromine was added to the mixture, followed by stirring at room temperature for 7 hours. The reaction mixture was extracted by ethyl acetate. The organic layer was washed with water dried over anhydrous magnesium sulfate, filtered, and concentrated under reduced pressure. Hexane was added to the residue, as a result, a crystal was formed. The crystal was collected to obtain 3.38 g of 4-bromo-3-(trifluoromethyl)-1H-pyrazole. 1H-NMR(CDCl3,TMS,delta(ppm)):7.72(1H,s)<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[205,131],"tags":[126],"class_list":["post-1596","post","type-post","status-publish","format-standard","hentry","category-20154-03-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nDiscovery of 20154-03-4<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 20154-03-4, name is 3-(Trifluoromethyl)-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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