{"id":1571,"date":"2021-01-26T05:33:12","date_gmt":"2021-01-25T21:33:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1571"},"modified":"2021-01-26T05:33:12","modified_gmt":"2021-01-25T21:33:12","slug":"the-important-role-of-92534-69-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1571","title":{"rendered":"The important role of 92534-69-5"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 92534-69-5, name is 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid, A new synthetic method of this compound is introduced below., Quality Control of 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid<\/a><\/p>\n

1-Methyl-4-nitroimidazole-5-carboxylic acid (or 1-methyl-4-nitropyrazole-5-carboxylic acid) (0.51 g, 3 mM, dry tetrahydrofuran (90 mL) and triethylamine (0.6 mL) were cooled to -10C. A solution of ethyl chloroformate (0.36 mL) in dry tetrahydrofuran (10 mL) was added to the resulting mixture and was stirred for further 30 min. The mixture of 2-(6-methoxy-1-methyl-9H-carbazol-2-yl)ethylamine 5 (0.75 g, 3 mM), tetrahydrofuran (90 mL) and triethylamine (0.6 mL) was added dropwise at -10C. The resulting mixture was left for 24 h to reach room temperature with stirring and evaporation under reduced pressure afforded a residue which was put into water (100 mL), alkalized with sodium hydrogen carbonate, and extracted with methylene chloride. The extract was dried over magnesium sulfate. After evaporation of the solvent, the solid residue was purified by column chromatography on silica gel and eluted with chloroform : methanol (9 : 1).<\/p>\n

The synthetic route of 92534-69-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 92534-69-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[328,131],"tags":[126],"class_list":["post-1571","post","type-post","status-publish","format-standard","hentry","category-92534-69-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 92534-69-5<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 92534-69-5, name is 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid, A new synthetic method of this compound is introduced below., Quality Control of 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1571\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of 92534-69-5\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 92534-69-5, name is 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid, A new synthetic method of this compound is introduced below., Quality Control of 1-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1571\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-25T21:33:12+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=1571\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=1571\",\"name\":\"The important role of 92534-69-5\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-01-25T21:33:12+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The important role of 92534-69-5","description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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