{"id":1552,"date":"2021-01-25T06:56:15","date_gmt":"2021-01-24T22:56:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1552"},"modified":"2021-01-25T06:56:15","modified_gmt":"2021-01-24T22:56:15","slug":"the-origin-of-a-common-compound-about-1820-80-0","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1552","title":{"rendered":"The origin of a common compound about 1820-80-0"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1820-80-0, name is 1H-Pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 1H-Pyrazol-3-amine<\/a><\/p>\n

To a stirred suspension of 118 (2.00g, 24.O7mmol) in concentrated HC1 (32mL) was added a solution ofNaNO2 (3.32g. 48.i4mmoi) in water (5mL) over 5 minutes at 0C. To the resulting orange reaction mixture was added a solution of KI (9.99g, 60 iSmmol) in water (l0mL) over 10 minutes. The reaction mixture was stirred at 0C for 30 minutes and then kept at 28C for another 2 hours, TLC showed the reaction was complete, then, solvent THF (3OmL) was added,followed by water (3OmL). The aqueous mixture was extracted with EtOAc (3 x8OmL) and the combined organic extracts were washed with Na2S2O3 (2 x4OmL), dried over Na2SO4, filtered and concentrated in vacuum to afford product 180 (200 g, crude), the crude product was used directly for the next step without purification.LCMS: m\/z, i94.9M+H)??.<\/p>\n

According to the analysis of related databases, 1820-80-0, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 1820-80-0, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[323,131],"tags":[145],"class_list":["post-1552","post","type-post","status-publish","format-standard","hentry","category-1820-80-0","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nThe origin of a common compound about 1820-80-0<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1820-80-0, name is 1H-Pyrazol-3-amine, This compound has unique chemical properties. 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