{"id":1535,"date":"2021-01-21T02:52:14","date_gmt":"2021-01-20T18:52:14","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1535"},"modified":"2021-01-21T02:52:14","modified_gmt":"2021-01-20T18:52:14","slug":"sources-of-common-compounds-25016-20-0","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1535","title":{"rendered":"Sources of common compounds: 25016-20-0"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 25016-20-0, name is 1-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 25016-20-0, Quality Control of 1-Methyl-1H-pyrazole-3-carboxylic acid<\/a><\/p>\n

Step 3: To solution of step 2 intermediate (6.0 g, 47.6 mmol) in CH2CI2 (50 mL) were added oxalyl chloride (6.12 mL, 71.4 mmol) and catalytic amount of DMF (0.5 mL) at 0C. The RM was stirred at rt for 2 h. The RM was concentrated under reduced pressure and residue was diluted with CH2CI2. NH3 gas was passed through RM at 0C for 30 min. After that the RM was concentrated under reduced pressure and residue was suspended in THF (50 ml) and filtered. The filtrate was concentrated under reduced pressure to yield the desired compound (3.5 g, 59%). LC-MS (Method 3): m\/z [M+H]+ = 126 (MW calc. = 125.13); R, = 0.76 min.<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[242,131],"tags":[126],"class_list":["post-1535","post","type-post","status-publish","format-standard","hentry","category-25016-20-0","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSources of common compounds: 25016-20-0<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 25016-20-0, name is 1-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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