{"id":1481,"date":"2021-01-14T01:36:14","date_gmt":"2021-01-13T17:36:14","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1481"},"modified":"2021-01-14T01:36:14","modified_gmt":"2021-01-13T17:36:14","slug":"the-important-role-of-326827-21-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1481","title":{"rendered":"The important role of 326827-21-8"},"content":{"rendered":"

326827-21-8, name is 3-Amino-5-cyclobutyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 3-Amino-5-cyclobutyl-1H-pyrazole<\/a><\/p>\n

Example 271: Preparation of 6-((4-((5-cydobutyl-lH-pyrazol-3-yl)amino)-5- (trifluorometh l) rimidin-2-yl)amino)-3,4-dihydroquinoli -2(lH)-one.6-((4-Chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)-3,4-dihydroquinolin-2(lH)-one (0.060 g, 0.175 mmol), 5-cyclobutyl-lH-pyrazol-3-amine (0.024 g, 0.175 mmol) and N-ethyl-N- isopropylpropan-2-amine (0.034 ml, 0.193 mmol) were mixed in DMF (2 ml). The mixture was microwaved at 130 C for 30 min and then concentrated. 14 mg of product was recovered after automated reverse phase chromatography (water- 10% THF in MeCN). MS calcd for[C2iH2oF3N70+H]+: 444.18 found 444.15.<\/p>\n

The synthetic route of 326827-21-8 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 326827-21-8 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[307,131],"tags":[126],"class_list":["post-1481","post","type-post","status-publish","format-standard","hentry","category-326827-21-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 326827-21-8<\/title>\n<meta name=\"description\" content=\"326827-21-8, name is 3-Amino-5-cyclobutyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 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