{"id":1456,"date":"2021-01-12T01:38:19","date_gmt":"2021-01-11T17:38:19","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1456"},"modified":"2021-01-12T01:38:19","modified_gmt":"2021-01-11T17:38:19","slug":"new-learning-discoveries-about-2458-26-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1456","title":{"rendered":"New learning discoveries about 2458-26-6"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2458-26-6, name is 3-Phenyl-1H-pyrazole, A new synthetic method of this compound is introduced below., HPLC of Formula: C9H8N2<\/a><\/p>\n

1.57 g of 3-phenylpyrazole was dissolved in 11 ml of N,N-dimethylformamide. To the resulting solution was added 0.50 g of 60% sodium hydride, and the entire mixture was stirred for 1.5 hours at room temperature. To this mixture was added a solution containing 2.90 g of the 1-tert-butoxycarbonylpiperidin-4-yl methanesulfonate dissolved in 2 ml of N,N-dimethylformamide, and the entire mixture was stirred for two hours at 50C, one hour at 70C, and then 3.5 hours at 100C. The reaction liquid was then poured into water, and extracted twice with ether. The organic layer was washed three times with water and dried over anhydrous magnesium sulfate, and the solvent was then removed by evaporation under reduced pressure. The residue was purified by silica gel column chromatography (developing solvent: hexane\/ethyl acetate = 4\/1 (volume ratio)), yielding 1.54 g of the target compound.<\/p>\n

The synthetic route of 2458-26-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 2458-26-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[164,131],"tags":[126],"class_list":["post-1456","post","type-post","status-publish","format-standard","hentry","category-2458-26-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about 2458-26-6<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New learning discoveries about 2458-26-6","description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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