{"id":1425,"date":"2021-01-11T09:19:23","date_gmt":"2021-01-11T01:19:23","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1425"},"modified":"2021-01-11T09:19:23","modified_gmt":"2021-01-11T01:19:23","slug":"some-tips-on-26621-44-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1425","title":{"rendered":"Some tips on 26621-44-3"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 26621-44-3, name is 3-Nitro-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Formula: C3H3N3O2<\/a><\/p>\n

To a stirred solution of 3-nitro-lH-pyrazole 94 (5.0 g, 44.24 mmol) in acetonitrile (50 mL) was added K2CO3 (12 g, 88.49 mmol) followed by 2-bromoethan-l-ol (5.4 g, 44.24 mmol) and the reaction mixture was stirred at 90 C for 16 h. Progress of the reaction was monitored by LC-MS. Volatiles were removed under reduced pressure and the crude residue thus obtained was diluted with ethyl acetate (150 mL) and water (100 mL). Organic layer was separated off and aqueous layer was further extracted with ethyl acetate (100 mL x 2). (1695) Combined organic layer was dried over sodium sulphate and evaporated under reduced pressure to get the crude residue which was purified by silica gel column chromatography (100-200 mesh) using 30% EtOAc in hexanes to afford 95 (4 g, 58%) as a pale yellow viscous oil. 1H NMR (400 MHz, DMSO-d6) delta 3.78 (q, J=5.38 Hz, 2H), 4.27 (t, 5.14J H=z, 2H), 5.00 (t, J5=.38 Hz, 1H), 7.03 (d, 2J.4=5 Hz, 1H), 7.99 (d, 2.45J H=z, 1H).<\/p>\n

According to the analysis of related databases, 26621-44-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 26621-44-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[163,131],"tags":[126],"class_list":["post-1425","post","type-post","status-publish","format-standard","hentry","category-26621-44-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSome tips on 26621-44-3<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 26621-44-3, name is 3-Nitro-1H-pyrazole, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Some tips on 26621-44-3","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 26621-44-3, name is 3-Nitro-1H-pyrazole, This compound has unique chemical properties. 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