{"id":1285,"date":"2020-12-25T10:57:49","date_gmt":"2020-12-25T02:57:49","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1285"},"modified":"2020-12-25T10:57:49","modified_gmt":"2020-12-25T02:57:49","slug":"analyzing-the-synthesis-route-of-55864-87-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1285","title":{"rendered":"Analyzing the synthesis route of 55864-87-4"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 55864-87-4, name is Ethyl 4-nitro-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., HPLC of Formula: C6H7N3O4<\/a><\/p>\n

a) A mixture of ethyl 4-NITRO-LH-PYRAZOLE-3-CARBOXYLATE (0. 685 g, 3.7 mmol) and 2- chloro-N- (3-fluorophenyl) acetamide (0.694 g, 3.7 mmol) and potassium carbonate (0.613 g, 4.44 mmol) in dimethyl formamide (10 ml) was stirred at room temperature for 20 hours. The mixture was evaporated and the residue was purified by silica gel chromatography eluting with a 8 to 10% mixture of ethyl acetate in dichloromethane to give ethyl 1- {2- [ (3- fluorophenyl) AMINO]-2-OXOETHYL}-4-NITRO-LH-PYRAZOLE-3-CARBOXYLATE (0.920 g, 74% yield): H-NMR (DMSO d6 TFA): 9.02 (s, 1H), 7.57 (d, 1H), 7.39 (q, 1H), 7.32 (d, 1H), 6.93 (t, 1H), 5.24 (s, 2H), 4.38 (q, 2H), 1.31 (t, 3H); MS (+ ve ESI): 337.17 (M+H) +.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[258,131],"tags":[126],"class_list":["post-1285","post","type-post","status-publish","format-standard","hentry","category-55864-87-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nAnalyzing the synthesis route of 55864-87-4<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 55864-87-4, name is Ethyl 4-nitro-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., HPLC of Formula: C6H7N3O4\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1285\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analyzing the synthesis route of 55864-87-4\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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