{"id":1250,"date":"2020-12-22T13:20:52","date_gmt":"2020-12-22T05:20:52","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1250"},"modified":"2020-12-22T13:20:52","modified_gmt":"2020-12-22T05:20:52","slug":"share-a-compound-28491-52-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1250","title":{"rendered":"Share a compound : 28491-52-3"},"content":{"rendered":"

Some common heterocyclic compound, 28491-52-3, name is 5-Amino-1H-pyrazol-3(2H)-one, molecular formula is C3H5N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Computed Properties of C3H5N3O<\/a><\/p>\n

A. 1,2,4,7-Tetrahydro-5-methyl-7-(3-nitro-phenyl)-2-oxopyrazolo[1,5,-a]pyrimidine-6carboxylic acid, 1-methylethyl ester A mixture of 3-amino-5-pyrazolone (3.57 g, 36.1 mmole) and 2-[(3-nitrophenyl)methylene]-3-oxobutanoic acid, 1-methylethyl ester (10 g, 36.1 mmole) in dry dimethylformamide (30 ml) was heated at 70 C. under argon for 24 hours. The reaction mixture was allowed to cool to room temperature and then diluted with ether. The resultant precipitate was filtered off and recrystallized from isopropanol to provide 4.23 g of the title A compound in crystalline form, m.p. 254-256 C. Analysis calc’d for C17 H18 N4 O5: C, 56.98; H, 5.06; N, 15.63; Found: C, 57.18; H, 5.10; N, 15.70.<\/p>\n

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 28491-52-3, its application will become more common.<\/p>\n","protected":false},"excerpt":{"rendered":"

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 28491-52-3, its application will become more common.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[243,131],"tags":[145],"class_list":["post-1250","post","type-post","status-publish","format-standard","hentry","category-28491-52-3","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nShare a compound : 28491-52-3<\/title>\n<meta name=\"description\" content=\"Some common heterocyclic compound, 28491-52-3, name is 5-Amino-1H-pyrazol-3(2H)-one, molecular formula is C3H5N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 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