{"id":12258,"date":"2023-02-13T04:17:49","date_gmt":"2023-02-12T20:17:49","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258"},"modified":"2023-02-13T04:17:49","modified_gmt":"2023-02-12T20:17:49","slug":"vega-salvador-et-al-published-their-research-in-european-journal-of-medicinal-chemistry-in-1988-cas-15953-73-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258","title":{"rendered":"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8"},"content":{"rendered":"<p>Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Product Details of 15953-73-8<\/a> This article mentions the following:<\/p>\n<p>Three series of new 3-(azol-1-yl)thienoisothiazole 1,1-dioxides, e.g., <strong>I<\/strong> (X = S, X<sup>1<\/sup> = CH; X = CH, CPh, X<sup>1<\/sup> = S: R, R<sup>1<\/sup>, R<sup>2<\/sup> = H, Cl, Me) were synthesized and tested for antiinflammatory, analgesic and antipyretic activity as well as for acute toxicity. Acetylsalicylic acid was used as the reference standard In the experiment, the researchers used many compounds, for example, 4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Product Details of 15953-73-8<\/a>).<\/p>\n<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Product Details of 15953-73-8<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Product Details of 15953-73-8<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[835,131],"tags":[128],"class_list":["post-12258","post","type-post","status-publish","format-standard","hentry","category-15953-73-8","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-12T20:17:49+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258\",\"name\":\"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2023-02-12T20:17:49+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12258#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives","description":"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258","og_locale":"en_US","og_type":"article","og_title":"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives","og_description":"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-02-12T20:17:49+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258","name":"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-02-12T20:17:49+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides was written by Vega, Salvador;Madronero, Ramon;Diaz, J. Antonio;Junquera, Francisco;Alonso, Javier;Darias, Victoriano;Bravo, Luis;Abdalah, Suzanne. And the article was included in European Journal of Medicinal Chemistry in 1988.Product Details of 15953-73-8 This article mentions the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=12258"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12258#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Vega, Salvador et al. published their research in European Journal of Medicinal Chemistry in 1988 | CAS: 15953-73-8"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12258","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12258"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12258\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}