{"id":12229,"date":"2023-02-09T10:52:25","date_gmt":"2023-02-09T02:52:25","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12229"},"modified":"2023-02-09T10:52:25","modified_gmt":"2023-02-09T02:52:25","slug":"liang-desheng-et-al-published-their-research-in-huaxue-xuebao-in-1982-cas-5334-39-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12229","title":{"rendered":"Liang, Desheng et al. published their research in Huaxue Xuebao in 1982 | CAS: 5334-39-4"},"content":{"rendered":"<p>The substituent effects on the chemical shifts of aromatic protons in heterocyclic compounds was written by Liang, Desheng;Lai, Zhugen;Xu, Guanzhi;Jiang, Mingqian. And the article was included in Huaxue Xuebao in 1982.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">Category: pyrazoles-derivatives<\/a> This article mentions the following:<\/p>\n<p>The substituent effect on the chem. shifts in <sup>3<\/sup>H NMR of aromatic heterocycles (e.g., furan, thiophene) depended on the electronic effect and the position of the substituents. An empirical formula was derived and the chem. shifts of &gt;700 aromatic protons were calculated to show a deviation of \u00b10.2-0.3 ppm. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">Category: pyrazoles-derivatives<\/a>).<\/p>\n<p>3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">Category: pyrazoles-derivatives<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">Category: pyrazoles-derivatives<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[216,131],"tags":[128],"class_list":["post-12229","post","type-post","status-publish","format-standard","hentry","category-5334-39-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Liang, Desheng et al. published their research in Huaxue Xuebao in 1982 | CAS: 5334-39-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"The substituent effects on the chemical shifts of aromatic protons in heterocyclic compounds was written by Liang, Desheng;Lai, Zhugen;Xu, Guanzhi;Jiang, Mingqian. And the article was included in Huaxue Xuebao in 1982.Category: pyrazoles-derivatives This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12229\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Liang, Desheng et al. published their research in Huaxue Xuebao in 1982 | CAS: 5334-39-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"The substituent effects on the chemical shifts of aromatic protons in heterocyclic compounds was written by Liang, Desheng;Lai, Zhugen;Xu, Guanzhi;Jiang, Mingqian. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Liang, Desheng et al. published their research in Huaxue Xuebao in 1982 | CAS: 5334-39-4 | pyrazoles-derivatives","description":"The substituent effects on the chemical shifts of aromatic protons in heterocyclic compounds was written by Liang, Desheng;Lai, Zhugen;Xu, Guanzhi;Jiang, Mingqian. 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