{"id":12224,"date":"2023-02-09T10:51:05","date_gmt":"2023-02-09T02:51:05","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12224"},"modified":"2023-02-09T10:51:05","modified_gmt":"2023-02-09T02:51:05","slug":"liu-weidong-et-al-published-their-research-in-nongyaoxue-xuebao-in-2004-cas-401-73-0","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12224","title":{"rendered":"Liu, Weidong et al. published their research in Nongyaoxue Xuebao in 2004 | CAS: 401-73-0"},"content":{"rendered":"<p>Synthesis and fungicidal activity of methyl N-methoxy-N-[2-(3-trifluoromethyl-1-substituted pyrazole-5-yloxymethylene)] phenylcarbamates was written by Liu, Weidong;Li, Jiangsheng;Li, Zhongying;Wang, Xiaoguang;Gao, Bida. And the article was included in Nongyaoxue Xuebao in 2004.<a href=\"https:\/\/www.ambeed.com\/products\/401-73-0.html\">Computed Properties of C4H3F3N2O<\/a> This article mentions the following:<\/p>\n<p>A series of novel Me N-methoxy-N-[2-(3-trifluoromethyl)-1-substituted pyrazole-5-yloxymethylene] phenylcarbamates <strong>I<\/strong> (R = Ph, 4-ClPh, 4-FPh, 2-MePh, 2,4-diMePh, 2,4-diClPh, 2-F-4-BrPh, 3,5-DiClPh, 3,4-diClPh, 2,4,5-triClPh, t-Bu, CH<sub>2<\/sub>CO<sub>2<\/sub>Et, Bn) were synthesized from 3-trifluoromethyl-1-substituted pyrazole-5-one and Me N-methoxy-N-(2-bromomethylphenyl) carbamates. All compounds were confirmed by <sup>1<\/sup>H NMR, IR and LC\/MS. The preliminary bioassays showed that some compounds had fungicidal activities to Pyricularia oryzae, Botrytis cinerea, and Erysiphe graminis under 50 mg\/L, for example, the inhibitory ratio of compound <strong>I<\/strong> (R = Bn) to P. oryzae was 94%. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)-1H-pyrazol-5(4H)-one (cas: 401-73-0<a href=\"https:\/\/www.ambeed.com\/products\/401-73-0.html\">Computed Properties of C4H3F3N2O<\/a>).<\/p>\n<p>3-(Trifluoromethyl)-1H-pyrazol-5(4H)-one (cas: 401-73-0) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.<a href=\"https:\/\/www.ambeed.com\/products\/401-73-0.html\">Computed Properties of C4H3F3N2O<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-(Trifluoromethyl)-1H-pyrazol-5(4H)-one (cas: 401-73-0) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.<a href=\"https:\/\/www.ambeed.com\/products\/401-73-0.html\">Computed Properties of C4H3F3N2O<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[834,131],"tags":[128],"class_list":["post-12224","post","type-post","status-publish","format-standard","hentry","category-401-73-0","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Liu, Weidong et al. published their research in Nongyaoxue Xuebao in 2004 | CAS: 401-73-0 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Synthesis and fungicidal activity of methyl N-methoxy-N-[2-(3-trifluoromethyl-1-substituted pyrazole-5-yloxymethylene)] phenylcarbamates was written by Liu, Weidong;Li, Jiangsheng;Li, Zhongying;Wang, Xiaoguang;Gao, Bida. 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