{"id":12208,"date":"2023-02-09T10:49:41","date_gmt":"2023-02-09T02:49:41","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12208"},"modified":"2023-02-09T10:49:41","modified_gmt":"2023-02-09T02:49:41","slug":"chande-madhukar-s-et-al-published-their-research-in-indian-journal-of-chemistry-in-2000-cas-51395-52-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12208","title":{"rendered":"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9"},"content":{"rendered":"<p>Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Product Details of 51395-52-9<\/a> This article mentions the following:<\/p>\n<p>3-Amino-2-alkyl\/arylimino-5-carbethoxy-thiazolidin-4-ones, 2-hydrazino-6-carbethoxy-4H,6H-1,3,4-thiadiazin-5-one, 2-hydrazino-7-substituted, 5,7-disubstituted-4H-pyrazolo[5,4-e]1,3,4-thiadiazines and 2-hydrazino-7-phenyl-4H-isoxazolo[5,4-e]-1,3,4-thiadiazine have been synthesized. The compounds have been characterized by chem. reactions, alternate syntheses and spectral data. In the experiment, the researchers used many compounds, for example, 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Product Details of 51395-52-9<\/a>).<\/p>\n<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Product Details of 51395-52-9<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Product Details of 51395-52-9<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[613,131],"tags":[128],"class_list":["post-12208","post","type-post","status-publish","format-standard","hentry","category-51395-52-9","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-09T02:49:41+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208\",\"name\":\"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2023-02-09T02:49:41+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:\",\"breadcrumb\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=12208#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives","description":"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208","og_locale":"en_US","og_type":"article","og_title":"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives","og_description":"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:","og_url":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-02-09T02:49:41+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208","url":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208","name":"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-02-09T02:49:41+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Synthesis of new heterocycles by using thiocarbohydrazide and thiosemicarbazides was written by Chande, Madhukar S.;Pankhi, Mohd Aslam;Ambhaikar, Shireesh B.. And the article was included in Indian Journal of Chemistry in 2000.Product Details of 51395-52-9 This article mentions the following:","breadcrumb":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/www.pyrazoles-derivatives.com\/?p=12208"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=12208#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Chande, Madhukar S. et al. published their research in Indian Journal of Chemistry in 2000 | CAS: 51395-52-9"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12208"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12208\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12208"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12208"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}