{"id":12199,"date":"2023-02-09T10:49:41","date_gmt":"2023-02-09T02:49:41","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199"},"modified":"2023-02-09T10:49:41","modified_gmt":"2023-02-09T02:49:41","slug":"katritzky-alan-r-et-al-published-their-research-in-arkivoc-gainesville-fl-united-states-in-2005-cas-54210-32-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199","title":{"rendered":"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1"},"content":{"rendered":"<p>Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.<a href=\"https:\/\/www.ambeed.com\/products\/54210-32-1.html\">Synthetic Route of C4H5N3O2<\/a> This article mentions the following:<\/p>\n<p>Direct nitration of a variety of furans, pyrroles, thiophenes, pyrazoles, imidazoles, isoxazoles and thiazoles (17 compounds) with nitric acid\/trifluoroacetic anhydride affords mononitro derivatives in average yield of 60%. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1<a href=\"https:\/\/www.ambeed.com\/products\/54210-32-1.html\">Synthetic Route of C4H5N3O2<\/a>).<\/p>\n<p>1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.<a href=\"https:\/\/www.ambeed.com\/products\/54210-32-1.html\">Synthetic Route of C4H5N3O2<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.<a href=\"https:\/\/www.ambeed.com\/products\/54210-32-1.html\">Synthetic Route of C4H5N3O2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[833,131],"tags":[128],"class_list":["post-12199","post","type-post","status-publish","format-standard","hentry","category-54210-32-1","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-09T02:49:41+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199\",\"name\":\"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2023-02-09T02:49:41+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12199#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives","description":"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199","og_locale":"en_US","og_type":"article","og_title":"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives","og_description":"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-02-09T02:49:41+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199","name":"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1 | pyrazoles-derivatives","isPartOf":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-02-09T02:49:41+00:00","author":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Direct nitration of five membered heterocycles was written by Katritzky, Alan R.;Scriven, Eric F. V.;Majumder, Suman;Akhmedova, Rena G.;Akhmedov, Novruz G.;Vakulenko, Anatoliy V.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2005.Synthetic Route of C4H5N3O2 This article mentions the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=12199"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12199#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"http:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2005 | CAS: 54210-32-1"}]},{"@type":"WebSite","@id":"http:\/\/www.pyrazoles-derivatives.com\/#website","url":"http:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12199"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/12199\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12199"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}