{"id":12189,"date":"2023-02-09T10:49:41","date_gmt":"2023-02-09T02:49:41","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12189"},"modified":"2023-02-09T10:49:41","modified_gmt":"2023-02-09T02:49:41","slug":"das-n-b-et-al-published-their-research-in-journal-of-the-indian-chemical-society-in-1979-cas-51395-52-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12189","title":{"rendered":"Das, N. B. et al. published their research in Journal of the Indian Chemical Society in 1979 | CAS: 51395-52-9"},"content":{"rendered":"<p>Synthesis of quinazolone and its derivatives as potential fungicides was written by Das, N. B.;Mittra, A. S.. And the article was included in Journal of the Indian Chemical Society in 1979.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Computed Properties of C4H5BrN2O<\/a> This article mentions the following:<\/p>\n<p>Condensation of 4-bromo-2-pyrazolin-5-one with 2-mercapto-3-aryl-4-quinazolones afforded quinazolones <strong>I<\/strong> (R = aryl,R<sup>1<\/sup> = H, Ph). They are fungitoxic against the rice blast pathogen <em>Pyricularia<\/em>\u00a0<em>oryzae<\/em> and brown leaf spot pathogen <em>Helminthosporium<\/em>\u00a0<em>oryzae<\/em>. In the experiment, the researchers used many compounds, for example, 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Computed Properties of C4H5BrN2O<\/a>).<\/p>\n<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Computed Properties of C4H5BrN2O<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">Computed Properties of C4H5BrN2O<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[613,131],"tags":[128],"class_list":["post-12189","post","type-post","status-publish","format-standard","hentry","category-51395-52-9","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Das, N. 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