{"id":12101,"date":"2023-01-30T07:04:01","date_gmt":"2023-01-29T23:04:01","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101"},"modified":"2023-01-30T07:04:01","modified_gmt":"2023-01-29T23:04:01","slug":"guo-huifeng-et-al-published-their-research-in-asian-journal-of-organic-chemistry-in-2021-cas-73387-46-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101","title":{"rendered":"Guo, Huifeng et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 73387-46-9"},"content":{"rendered":"<p>One-pot Synthesis of Substituted Pyrazoles from Propargyl Alcohols via Cyclocondensation of in situ-Generated \u03b1-Iodo Enones\/Enals and Hydrazine Hydrate was written by Guo, Huifeng;Zhang, Qinglin;Pan, Wanyong;Yang, Hong;Pei, Keke;Zhai, Jiulong;Li, Tiantian;Wang, Zhihai;Wang, Yan;Yin, Yan. And the article was included in Asian Journal of Organic Chemistry in 2021.<a href=\"https:\/\/www.ambeed.com\/products\/73387-46-9.html\">COA of Formula: C9H7BrN2<\/a> This article mentions the following:<\/p>\n<p>An efficient Bi(OTf)<sub>3<\/sub>-catalyzed transformation of unprotected propargylic alcs. has been developed, affording a general, one-pot approach to access diverse pyrazoles via sequential iodo-intercepted Meyer-Schuster rearrangement, cyclocondensation of NH<sub>2<\/sub>NH<sub>2<\/sub>\u00b7H<sub>2<\/sub>O and \u03b1-iodo enones\/enals generated in situ, and iodine elimination. This transformation tolerates a wide range of substrates and is reliable on a large scale. The high yields and convenient exptl. operations make it a valuable method for the construction of pyrazole derivatives In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9<a href=\"https:\/\/www.ambeed.com\/products\/73387-46-9.html\">COA of Formula: C9H7BrN2<\/a>).<\/p>\n<p>3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/73387-46-9.html\">COA of Formula: C9H7BrN2<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/73387-46-9.html\">COA of Formula: C9H7BrN2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[129],"class_list":["post-12101","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Guo, Huifeng et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 73387-46-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"One-pot Synthesis of Substituted Pyrazoles from Propargyl Alcohols via Cyclocondensation of in situ-Generated \u03b1-Iodo Enones\/Enals and Hydrazine Hydrate was written by Guo, Huifeng;Zhang, Qinglin;Pan, Wanyong;Yang, Hong;Pei, Keke;Zhai, Jiulong;Li, Tiantian;Wang, Zhihai;Wang, Yan;Yin, Yan. And the article was included in Asian Journal of Organic Chemistry in 2021.COA of Formula: C9H7BrN2 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12101\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Guo, Huifeng et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 73387-46-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"One-pot Synthesis of Substituted Pyrazoles from Propargyl Alcohols via Cyclocondensation of in situ-Generated \u03b1-Iodo Enones\/Enals and Hydrazine Hydrate was written by Guo, Huifeng;Zhang, Qinglin;Pan, Wanyong;Yang, Hong;Pei, Keke;Zhai, Jiulong;Li, Tiantian;Wang, Zhihai;Wang, Yan;Yin, Yan. 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And the article was included in Asian Journal of Organic Chemistry in 2021.COA of Formula: C9H7BrN2 This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-01-29T23:04:01+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101","name":"Guo, Huifeng et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 73387-46-9 | pyrazoles-derivatives","isPartOf":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-01-29T23:04:01+00:00","author":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"One-pot Synthesis of Substituted Pyrazoles from Propargyl Alcohols via Cyclocondensation of in situ-Generated \u03b1-Iodo Enones\/Enals and Hydrazine Hydrate was written by Guo, Huifeng;Zhang, Qinglin;Pan, Wanyong;Yang, Hong;Pei, Keke;Zhai, Jiulong;Li, Tiantian;Wang, Zhihai;Wang, Yan;Yin, Yan. And the article was included in Asian Journal of Organic Chemistry in 2021.COA of Formula: C9H7BrN2 This article mentions the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=12101"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=12101#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"http:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Guo, Huifeng et al. published their research in Asian Journal of Organic Chemistry in 2021 | CAS: 73387-46-9"}]},{"@type":"WebSite","@id":"http:\/\/www.pyrazoles-derivatives.com\/#website","url":"http:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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