{"id":12093,"date":"2023-01-30T07:04:01","date_gmt":"2023-01-29T23:04:01","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12093"},"modified":"2023-01-30T07:04:01","modified_gmt":"2023-01-29T23:04:01","slug":"chadha-vijay-k-et-al-published-their-research-in-journal-of-the-indian-chemical-society-in-1990-cas-51395-52-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12093","title":{"rendered":"Chadha, Vijay K. et al. published their research in Journal of the Indian Chemical Society in 1990 | CAS: 51395-52-9"},"content":{"rendered":"<p>Bridgehead nitrogen heterocycles. Part II. Reactions of 4-bromo-3-methyl-1-substituted-5-pyrazolones with 4-amino-3-mercapto-5-substituted-s-triazoles and cyclic thioureas was written by Chadha, Vijay K.;Sharma, G. R.. And the article was included in Journal of the Indian Chemical Society in 1990.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">HPLC of Formula: 51395-52-9<\/a> This article mentions the following:<\/p>\n<p>Bromomethylpyrazolones <strong>I<\/strong> (R = H, Ph) undergo cyclocondensation with aminomercaptotriazoles <strong>II<\/strong> (R<sup>1<\/sup> = Me, Et, Pr, Ph, 2-HOC<sub>6<\/sub>H<sub>4<\/sub>, 3-O<sub>2<\/sub>NC<sub>6<\/sub>H<sub>4<\/sub>) to give pyrazolotriazolothiadiazines <strong>III<\/strong>. <strong>I<\/strong> also reacts with cyclic thioureas, e.g. 2-mercapto-1-imidazoline gave pyrazoloimidazolothiazole <strong>IV<\/strong>. In the experiment, the researchers used many compounds, for example, 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">HPLC of Formula: 51395-52-9<\/a>).<\/p>\n<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">HPLC of Formula: 51395-52-9<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.<a href=\"https:\/\/www.ambeed.com\/products\/51395-52-9.html\">HPLC of Formula: 51395-52-9<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-12093","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chadha, Vijay K. et al. published their research in Journal of the Indian Chemical Society in 1990 | CAS: 51395-52-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Bridgehead nitrogen heterocycles. Part II. Reactions of 4-bromo-3-methyl-1-substituted-5-pyrazolones with 4-amino-3-mercapto-5-substituted-s-triazoles and cyclic thioureas was written by Chadha, Vijay K.;Sharma, G. R.. And the article was included in Journal of the Indian Chemical Society in 1990.HPLC of Formula: 51395-52-9 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12093\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chadha, Vijay K. et al. published their research in Journal of the Indian Chemical Society in 1990 | CAS: 51395-52-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Bridgehead nitrogen heterocycles. Part II. Reactions of 4-bromo-3-methyl-1-substituted-5-pyrazolones with 4-amino-3-mercapto-5-substituted-s-triazoles and cyclic thioureas was written by Chadha, Vijay K.;Sharma, G. R.. 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Part II. Reactions of 4-bromo-3-methyl-1-substituted-5-pyrazolones with 4-amino-3-mercapto-5-substituted-s-triazoles and cyclic thioureas was written by Chadha, Vijay K.;Sharma, G. R.. 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