{"id":12090,"date":"2023-01-30T07:04:01","date_gmt":"2023-01-29T23:04:01","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12090"},"modified":"2023-01-30T07:04:01","modified_gmt":"2023-01-29T23:04:01","slug":"habraken-clarisse-l-et-al-published-their-research-in-recueil-des-travaux-chimiques-des-pays-bas-in-1966-cas-5334-39-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12090","title":{"rendered":"Habraken, Clarisse L. et al. published their research in Recueil des Travaux Chimiques des Pays-Bas in 1966 | CAS: 5334-39-4"},"content":{"rendered":"<p>Pyrazoles.  I.  Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. And the article was included in Recueil des Travaux Chimiques des Pays-Bas in 1966.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">HPLC of Formula: 5334-39-4<\/a> This article mentions the following:<\/p>\n<p>Uv spectral data for 3(5)-methyl-4-nitropyrazole, 3,5-dimethyl-4-nitropyrazole, 1-methyl-4-nitropyrazole, and 1,3,-5-trimethyl-4-nitropyrazole, and ionization constants for the 1st 2 compounds are tabulated. The data indicate the absence of a steric effect of ortho-methyl groups in 4-nitropyrazoles. The findings corroborate the investigations of Ehrlich (CA 55, 2237f). In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">HPLC of Formula: 5334-39-4<\/a>).<\/p>\n<p>3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">HPLC of Formula: 5334-39-4<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/5334-39-4.html\">HPLC of Formula: 5334-39-4<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-12090","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Habraken, Clarisse L. et al. published their research in Recueil des Travaux Chimiques des Pays-Bas in 1966 | CAS: 5334-39-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Pyrazoles. I. Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. And the article was included in Recueil des Travaux Chimiques des Pays-Bas in 1966.HPLC of Formula: 5334-39-4 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12090\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Habraken, Clarisse L. et al. published their research in Recueil des Travaux Chimiques des Pays-Bas in 1966 | CAS: 5334-39-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Pyrazoles. I. Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. 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I. Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Habraken, Clarisse L. et al. published their research in Recueil des Travaux Chimiques des Pays-Bas in 1966 | CAS: 5334-39-4 | pyrazoles-derivatives","description":"Pyrazoles. I. Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. And the article was included in Recueil des Travaux Chimiques des Pays-Bas in 1966.HPLC of Formula: 5334-39-4 This article mentions the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=12090","og_locale":"en_US","og_type":"article","og_title":"Habraken, Clarisse L. et al. published their research in Recueil des Travaux Chimiques des Pays-Bas in 1966 | CAS: 5334-39-4 | pyrazoles-derivatives","og_description":"Pyrazoles. I. Ionization constants and ultraviolet spectra of 4-nitropyrazoles was written by Habraken, Clarisse L.;Van Woerkom, P. C. M.;De Wind, H. W.;Kallenberg, C. G. M.. 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