{"id":12080,"date":"2023-01-30T07:02:31","date_gmt":"2023-01-29T23:02:31","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=12080"},"modified":"2023-01-30T07:02:31","modified_gmt":"2023-01-29T23:02:31","slug":"chang-kwan-young-et-al-published-their-research-in-bioorganic-medicinal-chemistry-letters-in-2000-cas-45887-08-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=12080","title":{"rendered":"Chang, Kwan Young et al. published their research in Bioorganic &amp; Medicinal Chemistry Letters in 2000 | CAS: 45887-08-9"},"content":{"rendered":"<p>Synthesis and structure-activity relationships of quaternary ammonium cephalosporins with 3-pyrazolylpyridinium derivatives was written by Chang, Kwan Young;Kim, Sung Hoon;Nam, Ghilsoo;Seo, Jae Hong;Kim, Joong Hyup;Ha, Deok-Chan. And the article was included in Bioorganic &amp; Medicinal Chemistry Letters in 2000.<a href=\"https:\/\/www.ambeed.com\/products\/45887-08-9.html\">Reference of 45887-08-9<\/a> This article mentions the following:<\/p>\n<p>Cephalosporins with 3-pyrazolylpyridinium at C-3 position, which is supposed to exhibit synergic activity of ceftazidime and cefoselis, were synthesized and their antibacterial activity against Gram-pos. and Gram-neg. was inspected. In the experiment, the researchers used many compounds, for example, 3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9<a href=\"https:\/\/www.ambeed.com\/products\/45887-08-9.html\">Reference of 45887-08-9<\/a>).<\/p>\n<p>3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/45887-08-9.html\">Reference of 45887-08-9<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-(1H-Pyrazol-3-yl)pyridine (cas: 45887-08-9) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/45887-08-9.html\">Reference of 45887-08-9<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-12080","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chang, Kwan Young et al. published their research in Bioorganic &amp; Medicinal Chemistry Letters in 2000 | CAS: 45887-08-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Synthesis and structure-activity relationships of quaternary ammonium cephalosporins with 3-pyrazolylpyridinium derivatives was written by Chang, Kwan Young;Kim, Sung Hoon;Nam, Ghilsoo;Seo, Jae Hong;Kim, Joong Hyup;Ha, Deok-Chan. And the article was included in Bioorganic &amp; Medicinal Chemistry Letters in 2000.Reference of 45887-08-9 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12080\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chang, Kwan Young et al. published their research in Bioorganic &amp; Medicinal Chemistry Letters in 2000 | CAS: 45887-08-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Synthesis and structure-activity relationships of quaternary ammonium cephalosporins with 3-pyrazolylpyridinium derivatives was written by Chang, Kwan Young;Kim, Sung Hoon;Nam, Ghilsoo;Seo, Jae Hong;Kim, Joong Hyup;Ha, Deok-Chan. And the article was included in Bioorganic &amp; Medicinal Chemistry Letters in 2000.Reference of 45887-08-9 This article mentions the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=12080\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2023-01-29T23:02:31+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12080\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=12080\",\"name\":\"Chang, Kwan Young et al. published their research in Bioorganic &amp; Medicinal Chemistry Letters in 2000 | CAS: 45887-08-9 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2023-01-29T23:02:31+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Synthesis and structure-activity relationships of quaternary ammonium cephalosporins with 3-pyrazolylpyridinium derivatives was written by Chang, Kwan Young;Kim, Sung Hoon;Nam, Ghilsoo;Seo, Jae Hong;Kim, Joong Hyup;Ha, Deok-Chan. 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