{"id":1198,"date":"2020-12-08T09:38:09","date_gmt":"2020-12-08T01:38:09","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1198"},"modified":"2020-12-08T09:38:09","modified_gmt":"2020-12-08T01:38:09","slug":"brief-introduction-of-1260243-04-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1198","title":{"rendered":"Brief introduction of 1260243-04-6"},"content":{"rendered":"

1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 1260243-04-6<\/a><\/p>\n

5-Amino-1H-pyrazole-4-carboxylic acidEthyl ester (3.0 g, 19.3 mmol)In acetic acid (40 mL) and ethanol (10 mL)1,1,3,3-Tetramethoxypropane (3.48 g, 21.4 mmol) was added,The resulting reaction was stirred at 90 C overnight,Cool to room temperature,Concentrate under reduced pressure.The resulting residue was diluted with ethyl acetate (100 mL). The resulting solution was washed with saturated aqueous sodium bicarbonate (20 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (DCM \/ EA v \/ v) = 6\/1) to give the title compound as a light yellow solid (3.2 g, 85%).<\/p>\n

Statistics shows that 1260243-04-6 is playing an increasingly important role. we look forward to future research findings about Ethyl 5-amino-1H-pyrazole-4-carboxylate.<\/p>\n","protected":false},"excerpt":{"rendered":"

Statistics shows that 1260243-04-6 is playing an increasingly important role. we look forward to future research findings about Ethyl 5-amino-1H-pyrazole-4-carboxylate.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[213,131],"tags":[126],"class_list":["post-1198","post","type-post","status-publish","format-standard","hentry","category-1260243-04-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of 1260243-04-6<\/title>\n<meta name=\"description\" content=\"1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. 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