{"id":11970,"date":"2023-01-05T03:42:49","date_gmt":"2023-01-04T19:42:49","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11970"},"modified":"2023-01-05T03:42:49","modified_gmt":"2023-01-04T19:42:49","slug":"vicentini-chiara-b-et-al-published-their-research-in-journal-of-agricultural-and-food-chemistry-in-2002-cas-141459-53-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11970","title":{"rendered":"Vicentini, Chiara B. et al. published their research in Journal of Agricultural and Food Chemistry in 2002 | CAS: 141459-53-2"},"content":{"rendered":"<p>Development of new fungicides against Magnaporthe grisea: synthesis and biological activity of pyrazolo[3,4-d][1,3]thiazine, pyrazolo[1,5-c][1,3,5]thiadiazine, and pyrazolo[3,4-d]pyrimidine derivatives was written by Vicentini, Chiara B.;Forlani, Giuseppe;Manfrini, Maurizio;Romagnoli, Carlo;Mares, Donatella. And the article was included in Journal of Agricultural and Food Chemistry in 2002.<a href=\"https:\/\/www.ambeed.com\/products\/141459-53-2.html\">COA of Formula: C8H15N3<\/a> This article mentions the following:<\/p>\n<p>Some pyrazolo[3,4-d]pyrimidin-4(5H)-thione, pyrazolo[3,4-d][1,3]thiazin-4-one\/thione, and pyrazolo[1,5-c][1,3,5]thiadiazine-4-one\/thione derivatives were synthesized and screened for antifungal activity against the causal agent of rice blast disease, Magnaporthe grisea. In all cases a remarkable inhibition of fungal growth was found in the range from 10 to 200 \u03bcg mL<sup>-1<\/sup>. Several compounds were able to control mycelial growth at a rate of 10 \u03bcg mL<sup>-1<\/sup>, a concentration at which the reference compound tricyclazole was completely ineffective. At least in the case of the most active substance, at the same dose the growth of seedlings or cultured cells of rice was substantially unaffected. Results allowed definition of structural requirements either to maintain or to enhance mycotoxic activity. In the experiment, the researchers used many compounds, for example, 1-(tert-Butyl)-3-methyl-1H-pyrazol-5-amine (cas: 141459-53-2<a href=\"https:\/\/www.ambeed.com\/products\/141459-53-2.html\">COA of Formula: C8H15N3<\/a>).<\/p>\n<p>1-(tert-Butyl)-3-methyl-1H-pyrazol-5-amine (cas: 141459-53-2) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/141459-53-2.html\">COA of Formula: C8H15N3<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1-(tert-Butyl)-3-methyl-1H-pyrazol-5-amine (cas: 141459-53-2) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/141459-53-2.html\">COA of Formula: C8H15N3<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11970","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vicentini, Chiara B. et al. published their research in Journal of Agricultural and Food Chemistry in 2002 | CAS: 141459-53-2 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Development of new fungicides against Magnaporthe grisea: synthesis and biological activity of pyrazolo[3,4-d][1,3]thiazine, pyrazolo[1,5-c][1,3,5]thiadiazine, and pyrazolo[3,4-d]pyrimidine derivatives was written by Vicentini, Chiara B.;Forlani, Giuseppe;Manfrini, Maurizio;Romagnoli, Carlo;Mares, Donatella. And the article was included in Journal of Agricultural and Food Chemistry in 2002.COA of Formula: C8H15N3 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11970\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vicentini, Chiara B. et al. published their research in Journal of Agricultural and Food Chemistry in 2002 | CAS: 141459-53-2 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Development of new fungicides against Magnaporthe grisea: synthesis and biological activity of pyrazolo[3,4-d][1,3]thiazine, pyrazolo[1,5-c][1,3,5]thiadiazine, and pyrazolo[3,4-d]pyrimidine derivatives was written by Vicentini, Chiara B.;Forlani, Giuseppe;Manfrini, Maurizio;Romagnoli, Carlo;Mares, Donatella. 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And the article was included in Journal of Agricultural and Food Chemistry in 2002.COA of Formula: C8H15N3 This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11970","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-01-04T19:42:49+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11970","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11970","name":"Vicentini, Chiara B. et al. published their research in Journal of Agricultural and Food Chemistry in 2002 | CAS: 141459-53-2 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-01-04T19:42:49+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Development of new fungicides against Magnaporthe grisea: synthesis and biological activity of pyrazolo[3,4-d][1,3]thiazine, pyrazolo[1,5-c][1,3,5]thiadiazine, and pyrazolo[3,4-d]pyrimidine derivatives was written by Vicentini, Chiara B.;Forlani, Giuseppe;Manfrini, Maurizio;Romagnoli, Carlo;Mares, Donatella. 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