{"id":11927,"date":"2023-01-04T08:11:31","date_gmt":"2023-01-04T00:11:31","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11927"},"modified":"2023-01-04T08:11:31","modified_gmt":"2023-01-04T00:11:31","slug":"ocallaghan-c-n-et-al-published-their-research-in-proceedings-of-the-royal-irish-academy-in-1976-cas-934-48-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11927","title":{"rendered":"O&#8217;Callaghan, C. N. et al. published their research in Proceedings of the Royal Irish Academy in 1976 | CAS: 934-48-5"},"content":{"rendered":"<p>Reaction of hydrazine hydrate with 4-alkyl-1-cyanoacetylthiosemicarbazides was written by O&#8217;Callaghan, C. N.. And the article was included in Proceedings of the Royal Irish Academy, Section B:  Biological, Geological and Chemical Science in 1976.<a href=\"https:\/\/www.ambeed.com\/products\/934-48-5.html\">Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide<\/a> This article mentions the following:<\/p>\n<p>NCCH2CONHNHCSNHR (R = Me, Et, Pr, PhCH2) were cyclized by H2NNH2.H2O at 20\u00b0 to cyanomethyltriazolinethiones I, which at higher temperature were converted to II. In the experiment, the researchers used many compounds, for example, 3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5<a href=\"https:\/\/www.ambeed.com\/products\/934-48-5.html\">Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide<\/a>).<\/p>\n<p>3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/934-48-5.html\">Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.<a href=\"https:\/\/www.ambeed.com\/products\/934-48-5.html\">Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11927","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>O&#039;Callaghan, C. 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