{"id":11911,"date":"2023-01-04T04:59:16","date_gmt":"2023-01-03T20:59:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11911"},"modified":"2023-01-04T04:59:16","modified_gmt":"2023-01-03T20:59:16","slug":"morgentin-remy-et-al-published-their-research-in-synthetic-communications-in-2012-cas-55361-49-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11911","title":{"rendered":"Morgentin, Remy et al. published their research in Synthetic Communications in 2012 | CAS: 55361-49-4"},"content":{"rendered":"<p>Two-Directional Approach for the Rapid Synthesis of 2,4-Bis-Aminoaryl Pyridine Derivatives was written by Morgentin, Remy;Barlaam, Bernard;Foote, Kevin;Hassall, Lorraine;Hawkins, Janet;Jones, Clifford D.;Le Griffon, Antoine;Peru, Aurelien;Ple, Patrick. And the article was included in Synthetic Communications in 2012.<a href=\"https:\/\/www.ambeed.com\/products\/55361-49-4.html\">Category: pyrazoles-derivatives<\/a> This article mentions the following:<\/p>\n<p>We have developed two different approaches in parallel to rapidly access 2,4-bis(aminoaryl)pyridine compounds, e.g., <strong>I<\/strong>, from a common starting material. The C-4\/C-2 approach uses palladium-mediated coupling reactions to sequentially functionalize C-4 and then C-2. An alternative C-2\/C-4 route uses a regioselective SNAr reaction to first substitute at C-2 then subsequently at C-4 by a palladium-mediated reaction. Both approaches have been used successfully to provide a range of 2,4-bis(aminoaryl)pyridine compounds In the experiment, the researchers used many compounds, for example, 1-Ethyl-1H-pyrazol-3-amine (cas: 55361-49-4<a href=\"https:\/\/www.ambeed.com\/products\/55361-49-4.html\">Category: pyrazoles-derivatives<\/a>).<\/p>\n<p>1-Ethyl-1H-pyrazol-3-amine (cas: 55361-49-4) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/55361-49-4.html\">Category: pyrazoles-derivatives<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1-Ethyl-1H-pyrazol-3-amine (cas: 55361-49-4) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities.  The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/55361-49-4.html\">Category: pyrazoles-derivatives<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11911","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Morgentin, Remy et al. published their research in Synthetic Communications in 2012 | CAS: 55361-49-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Two-Directional Approach for the Rapid Synthesis of 2,4-Bis-Aminoaryl Pyridine Derivatives was written by Morgentin, Remy;Barlaam, Bernard;Foote, Kevin;Hassall, Lorraine;Hawkins, Janet;Jones, Clifford D.;Le Griffon, Antoine;Peru, Aurelien;Ple, Patrick. And the article was included in Synthetic Communications in 2012.Category: pyrazoles-derivatives This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11911\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Morgentin, Remy et al. published their research in Synthetic Communications in 2012 | CAS: 55361-49-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Two-Directional Approach for the Rapid Synthesis of 2,4-Bis-Aminoaryl Pyridine Derivatives was written by Morgentin, Remy;Barlaam, Bernard;Foote, Kevin;Hassall, Lorraine;Hawkins, Janet;Jones, Clifford D.;Le Griffon, Antoine;Peru, Aurelien;Ple, Patrick. 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And the article was included in Synthetic Communications in 2012.Category: pyrazoles-derivatives This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11911","og_site_name":"pyrazoles-derivatives","article_published_time":"2023-01-03T20:59:16+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11911","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11911","name":"Morgentin, Remy et al. published their research in Synthetic Communications in 2012 | CAS: 55361-49-4 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2023-01-03T20:59:16+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Two-Directional Approach for the Rapid Synthesis of 2,4-Bis-Aminoaryl Pyridine Derivatives was written by Morgentin, Remy;Barlaam, Bernard;Foote, Kevin;Hassall, Lorraine;Hawkins, Janet;Jones, Clifford D.;Le Griffon, Antoine;Peru, Aurelien;Ple, Patrick. 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