{"id":11908,"date":"2022-12-30T07:44:42","date_gmt":"2022-12-29T23:44:42","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11908"},"modified":"2022-12-30T07:44:42","modified_gmt":"2022-12-29T23:44:42","slug":"miyashita-akira-et-al-published-their-research-in-heterocycles-in-1990-cas-18213-75-7","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11908","title":{"rendered":"Miyashita, Akira et al. published their research in Heterocycles in 1990 | CAS: 18213-75-7"},"content":{"rendered":"<p>Studies on pyrazolo[3,4-d]pyrimidine derivatives.  XVIII.  Facile preparation of 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones was written by Miyashita, Akira;Iijima, Chihoko;Higashino, Takeo;Matsuda, Hideaki. And the article was included in Heterocycles in 1990.<a href=\"https:\/\/www.ambeed.com\/products\/18213-75-7.html\">Related Products of 18213-75-7<\/a> This article mentions the following:<\/p>\n<p>Reaction of 5-amino-1-phenyl-1<em>H<\/em>-pyrazole-4-carboxamide (<strong>I<\/strong>, R = Ph) with R<sup>1<\/sup>CO<sub>2<\/sub>R<sup>2<\/sup> (<strong>II<\/strong>, R<sup>1<\/sup> = H, Me, Et, Pr, Me<sub>2<\/sub>CH, PHCH<sub>2<\/sub>, CO<sub>2<\/sub>Et, Ph; R<sup>2<\/sup> = Me, Et) in the presence of EtONa-EtOH gave 1-phenylpyrazolopyrimidinones <strong>III<\/strong> (R = Ph). Similar treatment of <strong>I<\/strong> (R = Me) with <strong>II<\/strong> gave <strong>III<\/strong> (R = Me). In the experiment, the researchers used many compounds, for example, 5-Amino-1-methyl-1H-pyrazole-4-carboxamide (cas: 18213-75-7<a href=\"https:\/\/www.ambeed.com\/products\/18213-75-7.html\">Related Products of 18213-75-7<\/a>).<\/p>\n<p>5-Amino-1-methyl-1H-pyrazole-4-carboxamide (cas: 18213-75-7) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/18213-75-7.html\">Related Products of 18213-75-7<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>5-Amino-1-methyl-1H-pyrazole-4-carboxamide (cas: 18213-75-7) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/18213-75-7.html\">Related Products of 18213-75-7<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11908","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Miyashita, Akira et al. published their research in Heterocycles in 1990 | CAS: 18213-75-7 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Studies on pyrazolo[3,4-d]pyrimidine derivatives. XVIII. Facile preparation of 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones was written by Miyashita, Akira;Iijima, Chihoko;Higashino, Takeo;Matsuda, Hideaki. And the article was included in Heterocycles in 1990.Related Products of 18213-75-7 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11908\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Miyashita, Akira et al. published their research in Heterocycles in 1990 | CAS: 18213-75-7 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Studies on pyrazolo[3,4-d]pyrimidine derivatives. XVIII. Facile preparation of 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones was written by Miyashita, Akira;Iijima, Chihoko;Higashino, Takeo;Matsuda, Hideaki. 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