{"id":11898,"date":"2022-12-30T07:43:12","date_gmt":"2022-12-29T23:43:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11898"},"modified":"2022-12-30T07:43:12","modified_gmt":"2022-12-29T23:43:12","slug":"paveglio-guilherme-c-et-al-published-their-research-in-acs-sustainable-chemistry-engineering-in-2014-cas-73387-46-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11898","title":{"rendered":"Paveglio, Guilherme C. et al. published their research in ACS Sustainable Chemistry & Engineering in 2014 | CAS: 73387-46-9"},"content":{"rendered":"

How Mechanical and Chemical Features Affect the Green Synthesis of 1H-Pyrazoles in a Ball Mill was written by Paveglio, Guilherme C.;Longhi, Kelvis;Moreira, Dayse N.;Munchen, Taiana S.;Tier, Aniele. Z.;Gindri, Izabelle M.;Bender, Caroline R.;Frizzo, Clarissa P.;Zanatta, Nilo;Bonacorso, Helio G.;Martins, Marcos A. P.. And the article was included in ACS Sustainable Chemistry & Engineering in 2014.Computed Properties of C9H7BrN2<\/a> This article mentions the following:<\/p>\n

This work studied the chem. and mech. factors that affect cyclocondensation reactions in a ball mill. Chem. characteristics such as the use or non-use of a catalyst, amount of catalyst and reactants, and product formation, and the yield and mech. factors such as rotation frequency and the number, diameter, and material of the milling balls were evaluated. A rotation frequency of 450 rpm is efficient for energy transfer to the reactants because the conversion is higher at this rotation. The reaction was highly dependent on the time (3 min) and amount of p-TSA (p-toluenesulfonic acid) utilized as catalyst (10 mol %). Five steel balls of 10 mm were considered to be the ideal number for the efficient mixing of the particles. For this work, the ideal conditions determined were used for the green synthesis of a series of 1H-pyrazoles. In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9Computed Properties of C9H7BrN2<\/a>).<\/p>\n

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Computed Properties of C9H7BrN2<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor\u2013donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Computed Properties of C9H7BrN2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[129],"class_list":["post-11898","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"\nPaveglio, Guilherme C. et al. published their research in ACS Sustainable Chemistry & Engineering in 2014 | CAS: 73387-46-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"How Mechanical and Chemical Features Affect the Green Synthesis of 1H-Pyrazoles in a Ball Mill was written by Paveglio, Guilherme C.;Longhi, Kelvis;Moreira, Dayse N.;Munchen, Taiana S.;Tier, Aniele. Z.;Gindri, Izabelle M.;Bender, Caroline R.;Frizzo, Clarissa P.;Zanatta, Nilo;Bonacorso, Helio G.;Martins, Marcos A. P.. 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