{"id":11890,"date":"2022-12-30T07:43:12","date_gmt":"2022-12-29T23:43:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11890"},"modified":"2022-12-30T07:43:12","modified_gmt":"2022-12-29T23:43:12","slug":"stefani-helio-a-et-al-published-their-research-in-tetrahedron-letters-in-2005-cas-15953-73-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11890","title":{"rendered":"Stefani, Helio A. et al. published their research in Tetrahedron Letters in 2005 | CAS: 15953-73-8"},"content":{"rendered":"<p>A mild and efficient method for halogenation of 3,5-dimethyl pyrazoles by ultrasound irradiation using N-halosuccinimides was written by Stefani, Helio A.;Pereira, Claudio M. P.;Almeida, Roberta B.;Braga, Rodolpho C.;Guzen, Karla P.;Cella, Rodrigo. And the article was included in Tetrahedron Letters in 2005.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Recommanded Product: 4-Chloro-3,5-dimethyl-1H-pyrazole<\/a> This article mentions the following:<\/p>\n<p>The 4-halo-3,5-dimethyl pyrazoles were synthesized in good yields in short reaction times in the absence of a catalyst by reaction of 3,5-di-Me pyrazoles with N-halosuccinimides (NBS, NCS and NIS) under ultrasound irradiation Finally, the halogenation of pyrazoles with Br<sub>2<\/sub>, ICl and I<sub>2<\/sub> was showed in similar conditions. In the experiment, the researchers used many compounds, for example, 4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Recommanded Product: 4-Chloro-3,5-dimethyl-1H-pyrazole<\/a>).<\/p>\n<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Recommanded Product: 4-Chloro-3,5-dimethyl-1H-pyrazole<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Recommanded Product: 4-Chloro-3,5-dimethyl-1H-pyrazole<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11890","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Stefani, Helio A. et al. published their research in Tetrahedron Letters in 2005 | CAS: 15953-73-8 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"A mild and efficient method for halogenation of 3,5-dimethyl pyrazoles by ultrasound irradiation using N-halosuccinimides was written by Stefani, Helio A.;Pereira, Claudio M. P.;Almeida, Roberta B.;Braga, Rodolpho C.;Guzen, Karla P.;Cella, Rodrigo. And the article was included in Tetrahedron Letters in 2005.Recommanded Product: 4-Chloro-3,5-dimethyl-1H-pyrazole This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11890\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stefani, Helio A. et al. published their research in Tetrahedron Letters in 2005 | CAS: 15953-73-8 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"A mild and efficient method for halogenation of 3,5-dimethyl pyrazoles by ultrasound irradiation using N-halosuccinimides was written by Stefani, Helio A.;Pereira, Claudio M. P.;Almeida, Roberta B.;Braga, Rodolpho C.;Guzen, Karla P.;Cella, Rodrigo. 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