{"id":11860,"date":"2022-12-30T07:41:31","date_gmt":"2022-12-29T23:41:31","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860"},"modified":"2022-12-30T07:41:31","modified_gmt":"2022-12-29T23:41:31","slug":"elguero-jose-et-al-published-their-research-in-bulletin-de-la-societe-chimique-de-france-in-1966-cas-15953-73-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860","title":{"rendered":"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8"},"content":{"rendered":"<p>Azoles.  XIII.  Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Electric Literature of C5H7ClN2<\/a> This article mentions the following:<\/p>\n<p>The N.M.R. spectra of 180 pyrazoles in nonaqueous solvents (CDCl3, CCl4, C6H6, Me2SO, CF3CO2H) were analyzed. Classes represented were non-N-substituted, N-alkyl (especially N-Me), N-carboxamide, N-tosyl, N-Ph, N-p-nitrophenyl, N-(2,4-dinitrophenyl), and 2,4,6-trinitrophenyl pyrazoles. Chem. displacements (\u03c4) and coupling constants (J) were calculated and compared with literature values. Differences in values were attributed to substituents in ring positions 3, 4, and 5. Steric hindrance between the pyrazolic nucleus and aromatic substituents and the effect of C-Me groups on shielding of the pyrazolic protons was studied. 85 references. In the experiment, the researchers used many compounds, for example, 4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Electric Literature of C5H7ClN2<\/a>).<\/p>\n<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Electric Literature of C5H7ClN2<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.<a href=\"https:\/\/www.ambeed.com\/products\/15953-73-8.html\">Electric Literature of C5H7ClN2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[128],"class_list":["post-11860","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-12-29T23:41:31+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860\",\"name\":\"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-12-29T23:41:31+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11860#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives","description":"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860","og_locale":"en_US","og_type":"article","og_title":"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives","og_description":"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-12-29T23:41:31+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860","name":"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-12-29T23:41:31+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Azoles. XIII. Nuclear magnetic resonance spectra of pyrazoles was written by Elguero, Jose;Jacquier, Robert;Nguyen Tien Duc Hong Cung. And the article was included in Bulletin de la Societe Chimique de France in 1966.Electric Literature of C5H7ClN2 This article mentions the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=11860"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11860#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Elguero, Jose et al. published their research in Bulletin de la Societe Chimique de France in 1966 | CAS: 15953-73-8"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/11860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11860"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/11860\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}