{"id":11848,"date":"2022-12-05T07:32:40","date_gmt":"2022-12-04T23:32:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11848"},"modified":"2022-12-05T07:32:40","modified_gmt":"2022-12-04T23:32:40","slug":"lyalin-b-v-s-team-published-research-in-russian-chemical-bulletin-in-67-cas-105675-85-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11848","title":{"rendered":"Lyalin, B. V.&#8217;s team published research in Russian Chemical Bulletin  in 67 | CAS: 105675-85-2"},"content":{"rendered":"<p>Lyalin, B. V. published the artcile<b><i>Oxidative transformation of N-substituted 3-aminopyrazoles to azopyrazoles using electrogenerated bromine as a mediator<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/105675-85-2.html\">Quality Control of 105675-85-2<\/a>,  the publication is  Russian Chemical Bulletin (2018), 67(3), 510-516, database is CAplus.<\/p>\n<p>The one-pot process of anodic transformation of N-alkyl-3-aminopyrazoles into azopyrazoles <strong>I<\/strong> [R<sup>1<\/sup> = H, Me, Et; R<sup>2<\/sup> = H, Me; R<sup>3<\/sup> = Br, Me] under conditions of membraneless electrolysis in an aqueous solution of NaBr was studied for the first time. It was found that under these conditions the aminopyrazoles, which do not have a substituent at position 4, transform into the corresponding 4,4&#8242;-dibromoazopyrazoles. The corresponding yield was in the interval of 28-80%, depending on the structure of the products. The transformation of 4-substituted aminopyrazoles resulted in the formation of azopyrazoles in the yields lying within 62-86% when this process was implemented under conditions with the anodically generated Br<sub>2<\/sub> acting as a mediator. A convenient method of anodic synthesis of azopyrazoles in an aqueous medium without the use of additives of chem. oxidants was proposed. The process was environmentally sound and was characterized by a high atom efficiency (&gt;85%).<\/p>\n<p>Russian Chemical Bulletin published new progress about 105675-85-2. 105675-85-2 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Bromide,Amine, name is 4-Bromo-1-methyl-1H-pyrazol-5-amine, and the molecular formula is C4H6BrN3, <a href=\"https:\/\/www.ambeed.com\/products\/105675-85-2.html\">Quality Control of 105675-85-2<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,<br \/><a href=\"Pyrazole - Wikipedia\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Russian Chemical Bulletin published new progress about 105675-85-2. 105675-85-2 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Bromide,Amine, name is 4-Bromo-1-methyl-1H-pyrazol-5-amine, and the molecular formula is C4H6BrN3, <a href=\"https:\/\/www.ambeed.com\/products\/105675-85-2.html\">Quality Control of 105675-85-2<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[806,131],"tags":[717],"class_list":["post-11848","post","type-post","status-publish","format-standard","hentry","category-105675-85-2","category-pyrazoles-derivatives","tag-m-w150-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lyalin, B. V.&#039;s team published research in Russian Chemical Bulletin in 67 | CAS: 105675-85-2 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Lyalin, B. V. published the artcileOxidative transformation of N-substituted 3-aminopyrazoles to azopyrazoles using electrogenerated bromine as a mediator, Quality Control of 105675-85-2, the publication is Russian Chemical Bulletin (2018), 67(3), 510-516, database is CAplus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11848\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lyalin, B. V.&#039;s team published research in Russian Chemical Bulletin in 67 | CAS: 105675-85-2 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Lyalin, B. V. published the artcileOxidative transformation of N-substituted 3-aminopyrazoles to azopyrazoles using electrogenerated bromine as a mediator, Quality Control of 105675-85-2, the publication is Russian Chemical Bulletin (2018), 67(3), 510-516, database is CAplus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11848\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-12-04T23:32:40+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11848\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11848\",\"name\":\"Lyalin, B. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lyalin, B. 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