{"id":11821,"date":"2022-12-05T06:01:02","date_gmt":"2022-12-04T22:01:02","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11821"},"modified":"2022-12-05T06:01:02","modified_gmt":"2022-12-04T22:01:02","slug":"idemudia-omoruyi-g-s-team-published-research-in-bioinorganic-chemistry-and-applications-in-cas-4551-69-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11821","title":{"rendered":"Idemudia, Omoruyi G.&#8217;s team published research in Bioinorganic Chemistry and Applications  in  | CAS: 4551-69-3"},"content":{"rendered":"<p>Idemudia, Omoruyi G. published the artcile<b><i>Synthesis and characterization of bioactive acylpyrazolone sulfanilamides and their transition metal complexes: single crystal structure of 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one sulfanilamide<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/4551-69-3.html\">COA of Formula: C17H14N2O2<\/a>,  the publication is  Bioinorganic Chemistry and Applications (2015), 1-15, database is CAplus and MEDLINE.<\/p>\n<p>Two Schiff base ligands Ampp-Sn (<strong>1<\/strong>) and Bmpp-Sn (<strong>2<\/strong>), afforded by a condensation reaction between sulfanilamide and the resp. acylpyrazolone carbonyl precursors, their Mn(II), Co(II), Ni(II), and Cu(II) complexes prepared by the reaction of ligands and corresponding metal salts in aqueous solutions, were synthesized and then characterized by both anal. and spectroscopic methods, in a view to developing new improved bioactive materials with novel properties. From elemental anal., spectroscopic and TGA results, transition metal complexes, with octahedral geometry having two mols. of the bidentate keto-imine ligand each, are proposed. The single crystal structure of Bmpp-Sn according to x-ray crystallog. showed a keto-imine tautomer type of Schiff base, having three intramol. bonds, one short N2\u00b7\u00b7\u00b7H2\u00b7\u00b7\u00b7O3 hydrogen bond of 1.90 \u00c5 and two long C13\u00b7\u00b7\u00b7H13\u00b7\u00b7\u00b7O2 and C32\u00b7\u00b7\u00b7H32\u00b7\u00b7\u00b7O3 hydrogen bonds of 2.48 \u00c5. A moderate to low biol. activities were exhibited by synthesized compounds when compared with standard antimicrobial agents on screening the synthesized compounds against Staphylococcus aureus, Bacillus pumilus, Proteus vulgaris, and Aeromonas hydrophila for antibacterial activity and against free radical 1,1-diphenyl-2-picryl-hydrazyl (DPPH) for antioxidant activity.<\/p>\n<p>Bioinorganic Chemistry and Applications published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, <a href=\"https:\/\/www.ambeed.com\/products\/4551-69-3.html\">COA of Formula: C17H14N2O2<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,<br \/><a href=\"Pyrazole - Wikipedia\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bioinorganic Chemistry and Applications published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, <a href=\"https:\/\/www.ambeed.com\/products\/4551-69-3.html\">COA of Formula: C17H14N2O2<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[808,131],"tags":[740],"class_list":["post-11821","post","type-post","status-publish","format-standard","hentry","category-4551-69-3","category-pyrazoles-derivatives","tag-m-w250-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - 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