{"id":11808,"date":"2022-12-05T06:01:02","date_gmt":"2022-12-04T22:01:02","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11808"},"modified":"2022-12-05T06:01:02","modified_gmt":"2022-12-04T22:01:02","slug":"sudheer-reddy-v-s-team-published-research-in-russian-journal-of-bioorganic-chemistry-in-48-cas-724710-02-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11808","title":{"rendered":"Sudheer Reddy, V.’s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5"},"content":{"rendered":"

Sudheer Reddy, V. published the artcileSynthesis of Some New N-Substituted Imidazole Derivatives and Their In Vitro Antibacterial Investigation<\/i><\/b>, Product Details of C3H5BN2O2<\/a>, the publication is Russian Journal of Bioorganic Chemistry (2022), 48(3), 643-650, database is CAplus.<\/p>\n

Here the synthesis of N-substituted imidazole derivatives I<\/strong> (X = 3-MeOC6<\/sub>H4<\/sub>, 4-O2<\/sub>NC6<\/sub>H4<\/sub>, 3,5-F2<\/sub>C6<\/sub>H3<\/sub>, etc.) based on Suzuki coupling reaction of I<\/strong> (X = Br) with various arylboronic acids using Pd(dppf)Cl2<\/sub>\u00b7CH2<\/sub>Cl2<\/sub> as the catalyst and K2<\/sub>CO3<\/sub> as a base in 1,4-dioxane\/H2<\/sub>O (2 : 1) is described. The products were screened for their antibacterial activity against gram-pos. bacterial strains, Bacillus subtilis and Staphylococcus aureus, where the compounds I<\/strong> (X = 4-pyridinyl, 3-F-4-MeOC6<\/sub>H3<\/sub>, 3-NCC6<\/sub>H4<\/sub>, 3-FC6<\/sub>H4<\/sub>, 4-F-3-MeC6<\/sub>H3<\/sub>, 4-pyrazolyl) exhibited remarkable activity compared to the reference streptomycin.<\/p>\n

Russian Journal of Bioorganic Chemistry published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C14H20BClO2, Product Details of C3H5BN2O2<\/a>.<\/p>\n

Referemce:
https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Russian Journal of Bioorganic Chemistry published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C14H20BClO2, Product Details of C3H5BN2O2<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[801,131],"tags":[732],"class_list":["post-11808","post","type-post","status-publish","format-standard","hentry","category-724710-02-5","category-pyrazoles-derivatives","tag-m-w100-150"],"yoast_head":"\nSudheer Reddy, V.'s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Sudheer Reddy, V. published the artcileSynthesis of Some New N-Substituted Imidazole Derivatives and Their In Vitro Antibacterial Investigation, Product Details of C3H5BN2O2, the publication is Russian Journal of Bioorganic Chemistry (2022), 48(3), 643-650, database is CAplus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sudheer Reddy, V.'s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Sudheer Reddy, V. published the artcileSynthesis of Some New N-Substituted Imidazole Derivatives and Their In Vitro Antibacterial Investigation, Product Details of C3H5BN2O2, the publication is Russian Journal of Bioorganic Chemistry (2022), 48(3), 643-650, database is CAplus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-12-04T22:01:02+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808\",\"name\":\"Sudheer Reddy, V.'s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-12-04T22:01:02+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Sudheer Reddy, V. published the artcileSynthesis of Some New N-Substituted Imidazole Derivatives and Their In Vitro Antibacterial Investigation, Product Details of C3H5BN2O2, the publication is Russian Journal of Bioorganic Chemistry (2022), 48(3), 643-650, database is CAplus.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11808#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sudheer Reddy, V.’s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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