{"id":11582,"date":"2022-11-30T04:44:34","date_gmt":"2022-11-29T20:44:34","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11582"},"modified":"2022-11-30T04:44:34","modified_gmt":"2022-11-29T20:44:34","slug":"parmar-narsidas-j-s-team-published-research-in-bioorganic-medicinal-chemistry-letters-in-23-cas-14580-22-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11582","title":{"rendered":"Parmar, Narsidas J.’s team published research in Bioorganic & Medicinal Chemistry Letters in 23 | CAS: 14580-22-4"},"content":{"rendered":"

Parmar, Narsidas J. published the artcileAn efficient domino reaction in ionic liquid: Synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles<\/i><\/b>, COA of Formula: C10H9ClN2O<\/a>, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(6), 1656-1661, database is CAplus and MEDLINE.<\/p>\n

An improved domino\/Knoevenagel-hetero-Diels-Alder reaction of two new aldehyde substrates; 7-olefinoxy-coumarin-8-carbaldehyde and 2-alkensulfanyl-quinoline-3-carbaldehyde, with pyrazolones was studied in the ionic liquid triethylammonium acetate (TEAA), affording a series of pyrazolopyran annulated-pyrano-fused coumarins, and thiopyrano-fused quinolones. Besides acting as the catalyst, since no addnl. catalyst used, the ionic liquid TEAA also provided an easy recovery. In the polyheterocycles prepared, the cis-fusion of the two pyranyl rings has been inferred from 2D NMR COSY and NOESY experiments All are good antitubercular agents, as they are found active against Mycobacterium tuberculosis H37Rv, and antibacterial agents, as they are found active against three Gram-pos. (Streptococcus pneumoniae, Clostridium tetani, Bacillus subtilis) and three Gram-neg. (Salmonella typhi, Vibrio cholerae, Escherichia coli) bacteria.<\/p>\n

Bioorganic & Medicinal Chemistry Letters published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, COA of Formula: C10H9ClN2O<\/a>.<\/p>\n

Referemce:
https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Bioorganic & Medicinal Chemistry Letters published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, COA of Formula: C10H9ClN2O<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[799,131],"tags":[716],"class_list":["post-11582","post","type-post","status-publish","format-standard","hentry","category-14580-22-4","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"\nParmar, Narsidas J.'s team published research in Bioorganic & Medicinal Chemistry Letters in 23 | CAS: 14580-22-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Parmar, Narsidas J. published the artcileAn efficient domino reaction in ionic liquid: Synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles, COA of Formula: C10H9ClN2O, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(6), 1656-1661, database is CAplus and MEDLINE.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Parmar, Narsidas J.'s team published research in Bioorganic & Medicinal Chemistry Letters in 23 | CAS: 14580-22-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Parmar, Narsidas J. published the artcileAn efficient domino reaction in ionic liquid: Synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles, COA of Formula: C10H9ClN2O, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(6), 1656-1661, database is CAplus and MEDLINE.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-29T20:44:34+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582\",\"name\":\"Parmar, Narsidas J.'s team published research in Bioorganic & Medicinal Chemistry Letters in 23 | CAS: 14580-22-4 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-29T20:44:34+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Parmar, Narsidas J. published the artcileAn efficient domino reaction in ionic liquid: Synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles, COA of Formula: C10H9ClN2O, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(6), 1656-1661, database is CAplus and MEDLINE.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11582#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Parmar, Narsidas J.’s team published research in Bioorganic & Medicinal Chemistry Letters in 23 | CAS: 14580-22-4\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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