{"id":11539,"date":"2022-11-29T02:07:07","date_gmt":"2022-11-28T18:07:07","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11539"},"modified":"2022-11-29T02:07:07","modified_gmt":"2022-11-28T18:07:07","slug":"faid-allah-hassan-m-s-team-published-research-in-indian-journal-of-chemistry-section-b-organic-chemistry-including-medicinal-chemistry-in-27b-cas-71203-35-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11539","title":{"rendered":"Faid-Allah, Hassan M.&#8217;s team published research in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry  in 27B | CAS: 71203-35-5"},"content":{"rendered":"<p>Faid-Allah, Hassan M. published the artcile<b><i>Pyrazole derivatives with possible hypoglycemic activity<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/71203-35-5.html\">Synthetic Route of 71203-35-5<\/a>,  the publication is  Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1988), 27B(3), 245-9, database is CAplus.<\/p>\n<p>Condensation reaction of <em>p<\/em>-H<sub>2<\/sub>NSO<sub>2<\/sub>C<sub>6<\/sub>H<sub>4<\/sub>NHNH<sub>2<\/sub>.HCl with <em>p<\/em>-RC<sub>6<\/sub>H<sub>4<\/sub>CH:CHCOC<sub>6<\/sub>H<sub>4<\/sub>R<sup>1<\/sup>&#8211;<em>p<\/em> (R = H, R<sup>1<\/sup> = OMe, Cl, Br, NH<sub>2<\/sub>; R = MeO, R<sup>1<\/sup> = H) gave the corresponding hydrazones in the presence of NaOAc; in the absence of NaOAc, the products were pyrazolines <strong>I<\/strong> (R<sup>2<\/sup> = H). Oxidation of <strong>I<\/strong> with Br gave pyrazoles <strong>II<\/strong> (R<sup>2<\/sup> = H). Acylation and thioacylation of <strong>I<\/strong> and <strong>II<\/strong> with R<sup>3<\/sup>NCX (R<sup>3<\/sup> = Pr, Bu, Ph, cyclohexyl, X = O; R<sup>3<\/sup> = allyl, Ph, cyclohexyl, PhCH<sub>2<\/sub>, X = S) gave ureas and thioureas <strong>I<\/strong> and <strong>II<\/strong> [R<sup>2<\/sup> = CXNHR<sup>3<\/sup>]. Cyclocondensation of <strong>II<\/strong> (R<sup>2<\/sup> = CSNHR<sup>3<\/sup>) with Br(CH<sub>2<\/sub>)<em><sub>n<\/sub><\/em>CO<sub>2<\/sub>Et (<em>n<\/em> = 1,2) gave imino heterocycles <strong>III<\/strong>.<\/p>\n<p>Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 71203-35-5. 71203-35-5 belongs to pyrazoles-derivatives, auxiliary class GPCR\/G Protein,Ras, name is 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C22H21N3O3S, <a href=\"https:\/\/www.ambeed.com\/products\/71203-35-5.html\">Synthetic Route of 71203-35-5<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,<br \/><a href=\"Pyrazole - Wikipedia\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 71203-35-5. 71203-35-5 belongs to pyrazoles-derivatives, auxiliary class GPCR\/G Protein,Ras, name is 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C22H21N3O3S, <a href=\"https:\/\/www.ambeed.com\/products\/71203-35-5.html\">Synthetic Route of 71203-35-5<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[804,131],"tags":[785],"class_list":["post-11539","post","type-post","status-publish","format-standard","hentry","category-71203-35-5","category-pyrazoles-derivatives","tag-m-w400-450"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - 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