{"id":11519,"date":"2022-11-28T04:28:21","date_gmt":"2022-11-27T20:28:21","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11519"},"modified":"2022-11-28T04:28:21","modified_gmt":"2022-11-27T20:28:21","slug":"pandit-rameshwar-prasads-team-published-research-in-molecular-diversity-in-18-cas-14580-22-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11519","title":{"rendered":"Pandit, Rameshwar Prasad&#8217;s team published research in Molecular Diversity  in 18 | CAS: 14580-22-4"},"content":{"rendered":"<p>Pandit, Rameshwar Prasad published the artcile<b><i>Efficient one-pot synthesis of novel and diverse tetrahydroquinolines bearing pyranopyrazoles using organocatalyzed domino Knoevenagel\/hetero Diels-Alder reactions<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/14580-22-4.html\">Formula: C10H9ClN2O<\/a>,  the publication is  Molecular Diversity (2014), 18(1), 39-50, database is CAplus and MEDLINE.<\/p>\n<p>A new synthetic route to biol. interesting diverse tetrahydroquinoline derivatives bearing pyranopyrazole groups was developed and the synthesis of the target compounds was achieved by a reaction of pyrazolones and N,N-dialkylated aminobenzaldehyde derivatives in the presence of 1,2-Ethanediamine acetate (1:2) (EDDA, ethylenediammonium diacetate). The key strategy underlying the methodol. used was the domino Knoevenagel\/hetero Diels-Alder reaction. This synthetic method provides a variety of novel tetrahydroquinolines in good yields. The title compounds thus formed included a heterocyclic compound (<strong>I<\/strong>) and related substances. The synthesis of the target compounds was achieved by a reaction of 2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one derivatives with 2-[methyl(3-methyl-2-buten-1-yl)amino]benzaldehyde (prenylamine derivative), 2-[[(2<em>E<\/em>)-3,7-dimethyl-2,6-octadien-1-yl]methylamino]benzaldehyde (trans-geranylamine derivative), 2-[methyl[(2<em>E<\/em>,6<em>E<\/em>)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]amino]benzaldehyde (trans,trans-farnesylamine derivative).<\/p>\n<p>Molecular Diversity published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, <a href=\"https:\/\/www.ambeed.com\/products\/14580-22-4.html\">Formula: C10H9ClN2O<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,<br \/><a href=\"Pyrazole - Wikipedia\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Molecular Diversity published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, <a href=\"https:\/\/www.ambeed.com\/products\/14580-22-4.html\">Formula: C10H9ClN2O<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[799,131],"tags":[716],"class_list":["post-11519","post","type-post","status-publish","format-standard","hentry","category-14580-22-4","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - 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