{"id":11444,"date":"2022-11-25T10:27:25","date_gmt":"2022-11-25T02:27:25","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11444"},"modified":"2022-11-25T10:27:25","modified_gmt":"2022-11-25T02:27:25","slug":"doba-takahiros-team-published-research-in-nature-catalysis-in-2-cas-930-36-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11444","title":{"rendered":"Doba, Takahiro&#8217;s team published research in Nature Catalysis  in 2 | CAS: 930-36-9"},"content":{"rendered":"<p>Doba, Takahiro published the artcile<b><i>Homocoupling-free iron-catalyzed twofold C-H activation\/cross-couplings of aromatics via transient connection of reactants<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/930-36-9.html\">HPLC of Formula: 930-36-9<\/a>,  the publication is  Nature Catalysis (2019), 2(5), 400-406, database is CAplus.<\/p>\n<p>Herein, an efficient strategy was developed for the synthesis of biaryls and (aryl)alkenamides Ar(R)C=C(R<sup>1<\/sup>)C(O)NHAr<sup>1<\/sup> [R = Me; R<sup>1<\/sup> = Me; RR<sup>1<\/sup> = (CH<sub>2<\/sub>)<sub>4<\/sub>; Ar = 3,4-Cl<sub>2<\/sub>C<sub>6<\/sub>H<sub>3<\/sub>, 5-Ph-2-thienyl, benzothiophen-2-yl, etc.; Ar<sup>1<\/sup> = 8-quinolyl] via iron-catalyzed twofold C-H activation\/cross-coupling of arenes with alkenyl\/aryl carboxamides. A transient connection of two reactants by an anionic group appended to one reactant helped to achieve this goal under mildly oxidative iron-catalyzed conditions, through the formation of a productive heteroleptic R<sup>1<\/sup>-M-R<sup>2<\/sup> intermediate. An N-(quinolin-8-yl)amide anion was utilized for the temporary connection and cross-coupled a stoichiometric mixture of aromatics in high yield without any trace of homocoupling products. A short-step synthesis of several donor\/acceptor thiophene compounds and carbon\/sulfur-bridged flat conjugated systems illustrated the utility of this method to streamline organic synthesis.<\/p>\n<p>Nature Catalysis published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, <a href=\"https:\/\/www.ambeed.com\/products\/930-36-9.html\">HPLC of Formula: 930-36-9<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,<br \/><a href=\"Pyrazole - Wikipedia\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Catalysis published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, <a href=\"https:\/\/www.ambeed.com\/products\/930-36-9.html\">HPLC of Formula: 930-36-9<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[245,131],"tags":[784],"class_list":["post-11444","post","type-post","status-publish","format-standard","hentry","category-930-36-9","category-pyrazoles-derivatives","tag-m-w50-100"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - 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