{"id":11369,"date":"2022-11-24T03:05:04","date_gmt":"2022-11-23T19:05:04","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369"},"modified":"2022-11-24T03:05:04","modified_gmt":"2022-11-23T19:05:04","slug":"baba-hideos-team-published-research-in-bulletin-of-the-chemical-society-of-japan-in-42-cas-23286-70-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369","title":{"rendered":"Baba, Hideo’s team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6"},"content":{"rendered":"

Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine<\/i><\/b>, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.<\/p>\n

\u4f2a-Cyano-\u5c3e-methoxy-\u5c3e-alkyl (Me, Et, Pr, Bu, amyl, and iso-Bu) acrylic esters (I) react with hydrazine to give \u5c3e-hydrazino intermediates. The hydrazino group of these intermediates is cyclized preferentially between its terminal NH2 and the cyano group in a neutral or acidic medium to give 5-aminopyrazole derivatives and preferentially between the terminal NH2 and the ester group in the presence of a base to give 5-pyrazolinone derivatives When the \u5c3e-alkyl group of I is isopropyl, tertbutyl, etc., I affords only the 5-pyrazolinone derivatives in the reaction with hydrazine. The reactions of I with hydroxylamine gave 5-aminoisoxazole derivatives, but in the case of the \u5c3e-tert-butyl derivative of I, they gave 5-aminoisoxazole accompanied by the 5-isoxazolinone derivative<\/p>\n

Bulletin of the Chemical Society of Japan published new progress about 23286-70-6. 23286-70-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Ester, name is Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, and the molecular formula is C7H11N3O2, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>.<\/p>\n

Referemce:
https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Bulletin of the Chemical Society of Japan published new progress about 23286-70-6. 23286-70-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Ester, name is Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, and the molecular formula is C7H11N3O2, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[798,131],"tags":[717],"class_list":["post-11369","post","type-post","status-publish","format-standard","hentry","category-23286-70-6","category-pyrazoles-derivatives","tag-m-w150-200"],"yoast_head":"\nBaba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Baba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-23T19:05:04+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369\",\"name\":\"Baba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-23T19:05:04+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11369#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Baba, Hideo’s team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Baba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives","description":"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369","og_locale":"en_US","og_type":"article","og_title":"Baba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives","og_description":"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-11-23T19:05:04+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369","name":"Baba, Hideo's team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-11-23T19:05:04+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Baba, Hideo published the artcileReactions of \u4f2a-cyano-\u5c3e-methoxy-\u5c3e-alkylacrylic esters with hydrazine and hydroxylamine, Recommanded Product: Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Bulletin of the Chemical Society of Japan (1969), 42(6), 1653-9, database is CAplus.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=11369"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=11369#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Baba, Hideo’s team published research in Bulletin of the Chemical Society of Japan in 42 | CAS: 23286-70-6"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/11369","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11369"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/11369\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11369"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11369"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11369"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}