{"id":11308,"date":"2022-11-22T04:57:56","date_gmt":"2022-11-21T20:57:56","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11308"},"modified":"2022-11-22T04:57:56","modified_gmt":"2022-11-21T20:57:56","slug":"kobayashi-keijiro-et-al-published-their-research-in-chemistry-letters-in-2007-cas-61453-49-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11308","title":{"rendered":"Kobayashi, Keijiro et al. published their research in Chemistry Letters in 2007 | CAS: 61453-49-4"},"content":{"rendered":"<p>1,3-Dipolar cycloaddition of ethyl diazoacetate to alkynes in the pores of zeolite NaY was written by Kobayashi, Keijiro;Igura, Yuta;Imachi, Shouhei;Masui, Yoichi;Onaka, Makoto. And the article was included in Chemistry Letters in 2007.<a href=\"https:\/\/www.ambeed.com\/products\/61453-49-4.html\">Recommanded Product: Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate<\/a> The following contents are mentioned in the article:<\/p>\n<p>Zeolite NaY promotes 1,3-dipolar cycloaddition of Et diazoacetate to alkynes having an electron-withdrawing group to afford the corresponding functionalized pyrazoles in high yields. The activation of the dipolarophile inside the pores of NaY is proposed based on the <sup>13<\/sup>C MAS NMR anal. This study involved multiple reactions and reactants, such as Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate (cas: 61453-49-4<a href=\"https:\/\/www.ambeed.com\/products\/61453-49-4.html\">Recommanded Product: Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate<\/a>).<\/p>\n<p>Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate (cas: 61453-49-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/61453-49-4.html\">Recommanded Product: Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate (cas: 61453-49-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.<a href=\"https:\/\/www.ambeed.com\/products\/61453-49-4.html\">Recommanded Product: Ethyl 4-(hydroxymethyl)-1H-pyrazole-3-carboxylate<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[797,131],"tags":[128],"class_list":["post-11308","post","type-post","status-publish","format-standard","hentry","category-61453-49-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Kobayashi, Keijiro et al. published their research in Chemistry Letters in 2007 | CAS: 61453-49-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"1,3-Dipolar cycloaddition of ethyl diazoacetate to alkynes in the pores of zeolite NaY was written by Kobayashi, Keijiro;Igura, Yuta;Imachi, Shouhei;Masui, Yoichi;Onaka, Makoto. 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