{"id":11293,"date":"2022-11-22T04:56:43","date_gmt":"2022-11-21T20:56:43","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11293"},"modified":"2022-11-22T04:56:43","modified_gmt":"2022-11-21T20:56:43","slug":"antilla-jon-c-et-al-published-their-research-in-journal-of-organic-chemistry-in-2004-cas-741717-60-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11293","title":{"rendered":"Antilla, Jon C. et al. published their research in Journal of Organic Chemistry in 2004 | CAS: 741717-60-2"},"content":{"rendered":"<p>Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles was written by Antilla, Jon C.;Baskin, Jeremy M.;Barder, Timothy E.;Buchwald, Stephen L.. And the article was included in Journal of Organic Chemistry in 2004.<a href=\"https:\/\/www.ambeed.com\/products\/741717-60-2.html\">Application In Synthesis of Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate<\/a> The following contents are mentioned in the article:<\/p>\n<p>A copper-catalyzed N-arylation reaction of \u03c0-excessive nitrogen heterocycles is presented. The coupling of either aryl iodides or aryl bromides with common nitrogen heterocycles (pyrroles, pyrazoles, indazoles, imidazoles, and triazoles) was successfully performed in good yield with catalysts derived from diamine ligands and CuI. General conditions that tolerate functional groups such as aldehydes, ketones, alcs., primary amines, and nitriles on the aryl halide or heterocycle, were found. Hindered aryl halides or heterocycles were also found to be suitable substrates using the conditions reported herein. This study involved multiple reactions and reactants, such as Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate (cas: 741717-60-2<a href=\"https:\/\/www.ambeed.com\/products\/741717-60-2.html\">Application In Synthesis of Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate<\/a>).<\/p>\n<p>Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate (cas: 741717-60-2) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/741717-60-2.html\">Application In Synthesis of Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate (cas: 741717-60-2) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. <a href=\"https:\/\/www.ambeed.com\/products\/741717-60-2.html\">Application In Synthesis of Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[796,131],"tags":[129],"class_list":["post-11293","post","type-post","status-publish","format-standard","hentry","category-741717-60-2","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Antilla, Jon C. et al. published their research in Journal of Organic Chemistry in 2004 | CAS: 741717-60-2 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles was written by Antilla, Jon C.;Baskin, Jeremy M.;Barder, Timothy E.;Buchwald, Stephen L.. 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