{"id":11172,"date":"2022-11-21T05:02:08","date_gmt":"2022-11-20T21:02:08","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11172"},"modified":"2022-11-21T05:02:08","modified_gmt":"2022-11-20T21:02:08","slug":"zhu-you-quans-team-published-research-in-youji-huaxue-in-28-cas-23286-70-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11172","title":{"rendered":"Zhu, You-Quan’s team published research in Youji Huaxue in 28 | CAS: 23286-70-6"},"content":{"rendered":"

Zhu, You-Quan published the artcileDesign, synthesis and quantitative structure-activity relationship study of herbicidal of 3,4-dihydro-3-phenyl-4-oxopyrazolo[5,1-d<\/em>][1,2,3,5]tetrazine-8-carboxylic acid ethyl ester derivatives<\/i><\/b>, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>, the publication is Youji Huaxue (2008), 28(6), 1044-1049, database is CAplus.<\/p>\n

A method for the synthesis of the title compounds [i.e., 4-ethoxycarbonyl-1,7-dihydro-1-(substituted phenyl)-5-(un)substituted pyrazolo[5,1-d][1,2,3,5]tetrazin-7-one derivatives] is reported here. Their structures were confirmed by 1<\/sup>H NMR, IR spectra and elemental anal. A bioassay results showed that these compounds exhibited herbicidal activity. Quant. structure-activity relationship studies showed that their herbicidal activity was correlated with the molar refractivity (MR; optical refraction, molar refraction) and steric or hydrophobic physicochem. parameters, where the correlation coefficients were larger than 0.8. The herbicidal activity against Brassica campestris (Brassica rapa) was mainly affected by the MR for Ph substituents and the hydrophobic parameter (\u03c0) for the substituent on the pyrazolo[5,1-d<\/em>]-1,2,3,5-tetrazine group. When MR was about 1.452, the compound showed the highest herbicidal activity. The herbicidal activity against Echinochloa crus-galli was mainly related with Taft (Es) for the ortho-Ph substituent and the hydrophobic parameter (\u03c0) for the ortho-substituents and meta-substituents.<\/p>\n

Youji Huaxue published new progress about 23286-70-6. 23286-70-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Ester, name is Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, and the molecular formula is C13H15NO6S, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>.<\/p>\n

Referemce:
https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Youji Huaxue published new progress about 23286-70-6. 23286-70-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Ester, name is Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, and the molecular formula is C13H15NO6S, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[717],"class_list":["post-11172","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-m-w150-200"],"yoast_head":"\nZhu, You-Quan's team published research in Youji Huaxue in 28 | CAS: 23286-70-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Zhu, You-Quan published the artcileDesign, synthesis and quantitative structure-activity relationship study of herbicidal of 3,4-dihydro-3-phenyl-4-oxopyrazolo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid ethyl ester derivatives, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Youji Huaxue (2008), 28(6), 1044-1049, database is CAplus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zhu, You-Quan's team published research in Youji Huaxue in 28 | CAS: 23286-70-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Zhu, You-Quan published the artcileDesign, synthesis and quantitative structure-activity relationship study of herbicidal of 3,4-dihydro-3-phenyl-4-oxopyrazolo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid ethyl ester derivatives, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Youji Huaxue (2008), 28(6), 1044-1049, database is CAplus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-20T21:02:08+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172\",\"name\":\"Zhu, You-Quan's team published research in Youji Huaxue in 28 | CAS: 23286-70-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-20T21:02:08+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Zhu, You-Quan published the artcileDesign, synthesis and quantitative structure-activity relationship study of herbicidal of 3,4-dihydro-3-phenyl-4-oxopyrazolo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid ethyl ester derivatives, Safety of Ethyl 5-amino-3-methyl-1H-pyrazole-4-carboxylate, the publication is Youji Huaxue (2008), 28(6), 1044-1049, database is CAplus.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11172#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Zhu, You-Quan’s team published research in Youji Huaxue in 28 | CAS: 23286-70-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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