{"id":11115,"date":"2022-11-21T04:57:45","date_gmt":"2022-11-20T20:57:45","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11115"},"modified":"2022-11-21T04:57:45","modified_gmt":"2022-11-20T20:57:45","slug":"sabate-alduy-catherines-team-published-research-in-bulletin-de-la-societe-chimique-de-france-in-cas-37599-34-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11115","title":{"rendered":"Sabate-Alduy, Catherine’s team published research in Bulletin de la Societe Chimique de France in | CAS: 37599-34-1"},"content":{"rendered":"

Sabate-Alduy, Catherine published the artcile1,3-Dipolar cycloaddition of diazomethane Orientation of the addition of diazoalkanes to acetylenic compounds \u03b1-substituted with an alcohol or an ether group<\/i><\/b>, Product Details of C5H8N2O<\/a>, the publication is Bulletin de la Societe Chimique de France (1972), 2764-9, database is CAplus.<\/p>\n

The reaction of CH2N2 with acetylenic alcs. RR1CR2C\ue306CH (R and R1 = H, Me, Ph; (RR1) = (CH2)5; R2 = OH, NH2, OMe) was not stereospecific, giving 40-80% of the pyrazoles I and 20-60% of their isomers II (R3 = H). On the other hand the reaction with MeCHN2 was stereospecific, giving 80-100% I (R3 = Me). CH2N2 reacted with Me 3-(1-hydroxycyclohexyl)-propiolate to give 100% II [(RR1) = (CH2)5, R2 = OH, R3 = CO2Me , whereas with MeCHN2 a mixture of the isomers was obtained. Charge distribution calculations by the CNDO\/2 method confirm that the polarity of the acetylenic mol. determines the direction of the addition, rather than steric effects.<\/p>\n

Bulletin de la Societe Chimique de France published new progress about 37599-34-1. 37599-34-1 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Ether, name is 4-(methoxymethyl)-1H-pyrazole, and the molecular formula is C5H8N2O, Product Details of C5H8N2O<\/a>.<\/p>\n

Referemce:
https:\/\/en.wikipedia.org\/wiki\/Pyrazole<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Bulletin de la Societe Chimique de France published new progress about 37599-34-1. 37599-34-1 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Ether, name is 4-(methoxymethyl)-1H-pyrazole, and the molecular formula is C5H8N2O, Product Details of C5H8N2O<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[732],"class_list":["post-11115","post","type-post","status-publish","format-standard","hentry","category-pyrazoles-derivatives","tag-m-w100-150"],"yoast_head":"\nSabate-Alduy, Catherine's team published research in Bulletin de la Societe Chimique de France in | CAS: 37599-34-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Sabate-Alduy, Catherine published the artcile1,3-Dipolar cycloaddition of diazomethane Orientation of the addition of diazoalkanes to acetylenic compounds \u03b1-substituted with an alcohol or an ether group, Product Details of C5H8N2O, the publication is Bulletin de la Societe Chimique de France (1972), 2764-9, database is CAplus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sabate-Alduy, Catherine's team published research in Bulletin de la Societe Chimique de France in | CAS: 37599-34-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Sabate-Alduy, Catherine published the artcile1,3-Dipolar cycloaddition of diazomethane Orientation of the addition of diazoalkanes to acetylenic compounds \u03b1-substituted with an alcohol or an ether group, Product Details of C5H8N2O, the publication is Bulletin de la Societe Chimique de France (1972), 2764-9, database is CAplus.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-20T20:57:45+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115\",\"name\":\"Sabate-Alduy, Catherine's team published research in Bulletin de la Societe Chimique de France in | CAS: 37599-34-1 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-20T20:57:45+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Sabate-Alduy, Catherine published the artcile1,3-Dipolar cycloaddition of diazomethane Orientation of the addition of diazoalkanes to acetylenic compounds \u03b1-substituted with an alcohol or an ether group, Product Details of C5H8N2O, the publication is Bulletin de la Societe Chimique de France (1972), 2764-9, database is CAplus.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11115#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sabate-Alduy, Catherine’s team published research in Bulletin de la Societe Chimique de France in | CAS: 37599-34-1\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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