{"id":11034,"date":"2022-11-17T02:02:44","date_gmt":"2022-11-16T18:02:44","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=11034"},"modified":"2022-11-17T02:02:44","modified_gmt":"2022-11-16T18:02:44","slug":"hecht-sidney-m-s-team-published-research-in-journal-of-organic-chemistry-in-1975-cas-54385-49-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=11034","title":{"rendered":"Hecht, Sidney M.’s team published research in Journal of Organic Chemistry in 1975 | CAS: 54385-49-8"},"content":{"rendered":"

Hecht, Sidney M. published the artcileStructure determination of the N-methyl isomers of 5-amino-3,4-dicyanopyrazole and certain related pyrazolo[3,4-d]pyrimidines<\/i><\/b>, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile<\/a>, the main research area is pyrazoledicarbonitrile amino tautomerism; tautomerism aminopyrazoledicarbonitrile; pyrazolopyrimidine structure.<\/p>\n

Addnl. data considered in abstracting and indexing are available from a source cited in the original document. The position of N substitution of 4-aminopyrazolo[3, 4-d]pyrimidine derivatives was studied by chem. and spectroscopic techniques, and structures were assigned to the pyrazole precursors of these compounds The more abundant pyrazole resulting from treatment of tetracyanoethylene with MeNHNH2 was 3-amino-4, 5-dicyano-1-methylpyrazole (I) on the basis of its conversion to a pyrazolo[3,4-d]pyrimidine identical with authentic 4-amino-2-methylpyrazolo[3,4-d]pyrimidine, rather than with the authentic 1-methyl isomer. The assigned structure was verified by x-ray crystallog. determination of I. Because I was not expected to be the more abundant pyrazole, a mechanism was proposed to account for its formation. 13C NMR and uv data for 3-amino-4,5-dicyanopyrazole indicated that 5-amino-3,4-dicyano-1H-pyrazole was the major tautomer.<\/p>\n

Journal of Organic Chemistry published new progress about Tautomers. 54385-49-8 belongs to class pyrazoles-derivatives, name is 5-Amino-1H-pyrazole-3,4-dicarbonitrile, and the molecular formula is C5H3N5, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile<\/a>.<\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Journal of Organic Chemistry published new progress about Tautomers. 54385-49-8 belongs to class pyrazoles-derivatives, name is 5-Amino-1H-pyrazole-3,4-dicarbonitrile, and the molecular formula is C5H3N5, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[698,131],"tags":[732],"class_list":["post-11034","post","type-post","status-publish","format-standard","hentry","category-54385-49-8","category-pyrazoles-derivatives","tag-m-w100-150"],"yoast_head":"\nHecht, Sidney M.'s team published research in Journal of Organic Chemistry in 1975 | CAS: 54385-49-8 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Hecht, Sidney M. published the artcileStructure determination of the N-methyl isomers of 5-amino-3,4-dicyanopyrazole and certain related pyrazolo[3,4-d]pyrimidines, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile, the main research area is pyrazoledicarbonitrile amino tautomerism; tautomerism aminopyrazoledicarbonitrile; pyrazolopyrimidine structure.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hecht, Sidney M.'s team published research in Journal of Organic Chemistry in 1975 | CAS: 54385-49-8 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Hecht, Sidney M. published the artcileStructure determination of the N-methyl isomers of 5-amino-3,4-dicyanopyrazole and certain related pyrazolo[3,4-d]pyrimidines, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile, the main research area is pyrazoledicarbonitrile amino tautomerism; tautomerism aminopyrazoledicarbonitrile; pyrazolopyrimidine structure.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-16T18:02:44+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034\",\"name\":\"Hecht, Sidney M.'s team published research in Journal of Organic Chemistry in 1975 | CAS: 54385-49-8 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-16T18:02:44+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Hecht, Sidney M. published the artcileStructure determination of the N-methyl isomers of 5-amino-3,4-dicyanopyrazole and certain related pyrazolo[3,4-d]pyrimidines, Recommanded Product: 5-Amino-1H-pyrazole-3,4-dicarbonitrile, the main research area is pyrazoledicarbonitrile amino tautomerism; tautomerism aminopyrazoledicarbonitrile; pyrazolopyrimidine structure.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=11034#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Hecht, Sidney M.’s team published research in Journal of Organic Chemistry in 1975 | CAS: 54385-49-8\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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