{"id":10979,"date":"2022-11-15T03:38:41","date_gmt":"2022-11-14T19:38:41","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10979"},"modified":"2022-11-15T03:38:41","modified_gmt":"2022-11-14T19:38:41","slug":"johnson-matthew-p-s-team-published-research-in-journal-of-the-chemical-society-perkin-transactions-12-organic-and-bio-organic-chemistry-in-1985-01-31-cas-27412-71-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10979","title":{"rendered":"Johnson, Matthew P.&#8217;s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry  in 1985-01-31 | CAS: 27412-71-1"},"content":{"rendered":"<p>Johnson, Matthew P. published the artcile<b><i>Azo dienophiles. Diels-Alder reactions of 4-phenyl-1,2,4-triazole-3,5-dione and 5-phenylpyrazol-3-one with functionalized dienes<\/i><\/b>,  <a href=\"https:\/\/www.ambeed.com\/products\/27412-71-1.html\">Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one<\/a>,  the main research area is  Diels Alder phenyltriazoledione phenylpyrazolone diene; triazoledione phenyl Diels Alder diene; pyrazolone phenyl Diels Alder diene; regioselectivity Diels Alder phenylpyrazolone acetoxybutadiene.<\/p>\n<p>The title triazoledione (I) underwent Diels-Alder reactions with a variety of dienes. E.g., reaction of [ICH2C(:CH2)]2 with I in CH2Cl2 at -50\u00b0 for 15 min then -20\u00b0 overnight gave 60% adduct II (R = R3 = iodo, R1R2 = bond) (III). Reduction of III with a Zn-Cu couple gave 97% II (RR1 = R2R3 = bond) which in turn reacted with a variety of dienophiles, including I, in a tandem Diels-Alder reaction. 5-Phenylpyrazol-3-one, generated in situ by oxidation of the corresponding pyrazolinone with Pb(OAc)4, also underwent a variety of Diels-Alder reactions, including regioselective reaction with AcOCH:CHCH:CH2 in CH2Cl2 to give 67% pyrazolopyridazine IV.<\/p>\n<p>Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry published new progress about Diels-Alder reaction. 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, <a href=\"https:\/\/www.ambeed.com\/products\/27412-71-1.html\">Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry published new progress about Diels-Alder reaction. 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, <a href=\"https:\/\/www.ambeed.com\/products\/27412-71-1.html\">Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[678,131],"tags":[717],"class_list":["post-10979","post","type-post","status-publish","format-standard","hentry","category-27412-71-1","category-pyrazoles-derivatives","tag-m-w150-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Johnson, Matthew P.&#039;s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry in 1985-01-31 | CAS: 27412-71-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Johnson, Matthew P. published the artcileAzo dienophiles. Diels-Alder reactions of 4-phenyl-1,2,4-triazole-3,5-dione and 5-phenylpyrazol-3-one with functionalized dienes, Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one, the main research area is Diels Alder phenyltriazoledione phenylpyrazolone diene; triazoledione phenyl Diels Alder diene; pyrazolone phenyl Diels Alder diene; regioselectivity Diels Alder phenylpyrazolone acetoxybutadiene.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Johnson, Matthew P.&#039;s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry in 1985-01-31 | CAS: 27412-71-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Johnson, Matthew P. published the artcileAzo dienophiles. Diels-Alder reactions of 4-phenyl-1,2,4-triazole-3,5-dione and 5-phenylpyrazol-3-one with functionalized dienes, Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one, the main research area is Diels Alder phenyltriazoledione phenylpyrazolone diene; triazoledione phenyl Diels Alder diene; pyrazolone phenyl Diels Alder diene; regioselectivity Diels Alder phenylpyrazolone acetoxybutadiene.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-14T19:38:41+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979\",\"name\":\"Johnson, Matthew P.'s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry in 1985-01-31 | CAS: 27412-71-1 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-14T19:38:41+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Johnson, Matthew P. published the artcileAzo dienophiles. Diels-Alder reactions of 4-phenyl-1,2,4-triazole-3,5-dione and 5-phenylpyrazol-3-one with functionalized dienes, Recommanded Product: 5-Phenyl-1H-pyrazol-3(2H)-one, the main research area is Diels Alder phenyltriazoledione phenylpyrazolone diene; triazoledione phenyl Diels Alder diene; pyrazolone phenyl Diels Alder diene; regioselectivity Diels Alder phenylpyrazolone acetoxybutadiene.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10979#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Johnson, Matthew P.&#8217;s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry in 1985-01-31 | CAS: 27412-71-1\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Johnson, Matthew P.'s team published research in Journal of the Chemical Society, Perkin Transactions 12: Organic and Bio-Organic Chemistry in 1985-01-31 | CAS: 27412-71-1 | pyrazoles-derivatives","description":"Johnson, Matthew P. published the artcileAzo dienophiles. 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