{"id":10890,"date":"2022-11-02T11:01:04","date_gmt":"2022-11-02T03:01:04","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10890"},"modified":"2022-11-02T11:01:04","modified_gmt":"2022-11-02T03:01:04","slug":"wilson-kevin-j-et-al-published-their-patent-in-2014-cas-215610-30-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10890","title":{"rendered":"Wilson, Kevin J. et al. published their patent in 2014 |CAS: 215610-30-3"},"content":{"rendered":"

On April 3, 2014, Wilson, Kevin J.; Witter, David J.; Daniels, Matthew H.; Angeles, Angie R.; Siliphaivanh, Phieng; Sloman, David; O’Boyle, Brendan; Falcone, Danielle; White, Catherine; Ferguson, Ron; Zhou, Wei; Lipford, Kathryn; Mansoor, Umar Faruk; Fevrier, Salem; Huang, Xianhai; Kurukulasuriya, Ravi; Richard, Judson E.; Tang, Shuyi; Boyce, Christopher; Kozlowski, Joseph; Bakshi, Raman Kumar; Karunakaran, Ganesh Babu published a patent.Electric Literature of 215610-30-3<\/a> The title of the patent was Preparation of pyrazolopyridinyl ureas as ERK inhibitors. And the patent contained the following:<\/p>\n

The title compounds I [R1 = OR4, S(O)tR5; t = 0-2; R2 = H, alkyl; alkyl-O-alkyl, alkylaryl, etc.; R4 = alkyl-O-alkyl, alkylaryl, etc.; R5 = alkyl, alkyl-O-alkyl; R10, R11 = H, halo, alkyl, etc.] which are ERK inhibitors useful in treating cancer, were prepared E.g., a multi-step synthesis of (1R)-II, starting from Me 4,6-dichloropyridine-3-carboxylate and hydrazine, was described. Exemplified compounds I were tested in human ERK2 activity assay (data given). Pharmaceutical compositions comprising compound I, alone or in combination with an effective amount of at least one chemotherapeutic agent, were disclosed. The experimental process involved the reaction of 5-Methoxy-1H-pyrazole(cas: 215610-30-3).Electric Literature of 215610-30-3<\/a><\/p>\n

The Article related to pyrazolopyridinyl urea preparation erk inhibitor antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Electric Literature of 215610-30-3<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

The Article related to pyrazolopyridinyl urea preparation erk inhibitor antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Electric Literature of 215610-30-3<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[279,131],"tags":[743],"class_list":["post-10890","post","type-post","status-publish","format-standard","hentry","category-215610-30-3","category-pyrazoles-derivatives","tag-0-100"],"yoast_head":"\nWilson, Kevin J. et al. published their patent in 2014 |CAS: 215610-30-3 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"On April 3, 2014, Wilson, Kevin J.; Witter, David J.; Daniels, Matthew H.; Angeles, Angie R.; Siliphaivanh, Phieng; Sloman, David; O'Boyle, Brendan; Falcone, Danielle; White, Catherine; Ferguson, Ron; Zhou, Wei; Lipford, Kathryn; Mansoor, Umar Faruk; Fevrier, Salem; Huang, Xianhai; Kurukulasuriya, Ravi; Richard, Judson E.; Tang, Shuyi; Boyce, Christopher; Kozlowski, Joseph; Bakshi, Raman Kumar; Karunakaran, Ganesh Babu published a patent.Electric Literature of 215610-30-3 The title of the patent was Preparation of pyrazolopyridinyl ureas as ERK inhibitors. And the patent contained the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10890\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Wilson, Kevin J. et al. published their patent in 2014 |CAS: 215610-30-3 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"On April 3, 2014, Wilson, Kevin J.; Witter, David J.; Daniels, Matthew H.; Angeles, Angie R.; Siliphaivanh, Phieng; Sloman, David; O'Boyle, Brendan; Falcone, Danielle; White, Catherine; Ferguson, Ron; Zhou, Wei; Lipford, Kathryn; Mansoor, Umar Faruk; Fevrier, Salem; Huang, Xianhai; Kurukulasuriya, Ravi; Richard, Judson E.; Tang, Shuyi; Boyce, Christopher; Kozlowski, Joseph; Bakshi, Raman Kumar; Karunakaran, Ganesh Babu published a patent.Electric Literature of 215610-30-3 The title of the patent was Preparation of pyrazolopyridinyl ureas as ERK inhibitors. 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