{"id":10889,"date":"2022-11-02T11:01:04","date_gmt":"2022-11-02T03:01:04","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889"},"modified":"2022-11-02T11:01:04","modified_gmt":"2022-11-02T03:01:04","slug":"cho-won-je-et-al-published-their-patent-in-2021-cas-36640-53-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889","title":{"rendered":"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6"},"content":{"rendered":"<p>On September 7, 2021, Cho, Won Je published a patent.<a href=\"https:\/\/www.ambeed.com\/products\/36640-53-6.html\">Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde<\/a> The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:<\/p>\n<p>The present invention relates to a novel pyrazolecarboxamide carboxamide compound I [R1 = H, 3-OMe, 3,4-(OMe)2, 4-Me; R2 = H, CF3, NH2; OR3 = meta-(3-pyridinyloxy), para-(4-isopropylphenyl), para-(2-methoxy-4-methylphenyl), etc.] and a composition for preventing or treating metabolic diseases, wherein the composition is a potent and selective estrogen-related receptor (ERR) \u03b3 inverse agonist with excellent selectivity and since it shows affinity, it can be effectively used for treatment of metabolic diseases. For example, II was prepared and exhibited IC50 of 1.33\u03bcM against estrogen-related receptor (ERR) \u03b3. The experimental process involved the reaction of 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde(cas: 36640-53-6).<a href=\"https:\/\/www.ambeed.com\/products\/36640-53-6.html\">Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde<\/a><\/p>\n<p>The Article related to preparation pyrazolecarboxamide treatment metabolic disease, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.<a href=\"https:\/\/www.ambeed.com\/products\/36640-53-6.html\">Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Article related to preparation pyrazolecarboxamide treatment metabolic disease, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.<a href=\"https:\/\/www.ambeed.com\/products\/36640-53-6.html\">Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[762,131],"tags":[129],"class_list":["post-10889","post","type-post","status-publish","format-standard","hentry","category-36640-53-6","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-02T03:01:04+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889\",\"name\":\"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-02T03:01:04+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10889#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives","description":"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889","og_locale":"en_US","og_type":"article","og_title":"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives","og_description":"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-11-02T03:01:04+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889","name":"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6 | pyrazoles-derivatives","isPartOf":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-11-02T03:01:04+00:00","author":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"On September 7, 2021, Cho, Won Je published a patent.Name: 3-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde The title of the patent was Preparation of pyrazolecarboxamide for preventing or treating metabolic disease. And the patent contained the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=10889"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10889#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"http:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Cho, Won Je et al. published their patent in 2021 |CAS: 36640-53-6"}]},{"@type":"WebSite","@id":"http:\/\/www.pyrazoles-derivatives.com\/#website","url":"http:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10889","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10889"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10889\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10889"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10889"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10889"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}