{"id":10813,"date":"2022-11-02T03:24:18","date_gmt":"2022-11-01T19:24:18","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813"},"modified":"2022-11-02T03:24:18","modified_gmt":"2022-11-01T19:24:18","slug":"lancellotti-patrizio-et-al-published-their-patent-in-2019-cas-85426-79-5-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813","title":{"rendered":"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5"},"content":{"rendered":"<p>On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.<a href=\"https:\/\/www.ambeed.com\/products\/85426-79-5.html\">Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine<\/a> The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:<\/p>\n<p>Title compounds I [each X independently = N, CH, C(alkyl), etc.; Y = O or S; R1 and R2 independently = (un)substituted alkyl, alkenyl, aryl, etc.; each R3 independently = H, halo, OH, NO2, etc.; with provisions], and their pharmaceutically acceptable salts, are prepared and disclosed as antibacterial agents. Thus, e.g., II was prepared by a multistep procedure (preparation given). Select I were evaluated for antibacterial effects on S. epidermidis (ATCC25904), e.g., II demonstrated a minimal inhibitory concentration of 20-25 \u03bcM. The experimental process involved the reaction of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(cas: 85426-79-5).<a href=\"https:\/\/www.ambeed.com\/products\/85426-79-5.html\">Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine<\/a><\/p>\n<p>The Article related to pyrimidine preparation antibacterial agent, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.<a href=\"https:\/\/www.ambeed.com\/products\/85426-79-5.html\">Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Article related to pyrimidine preparation antibacterial agent, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.<a href=\"https:\/\/www.ambeed.com\/products\/85426-79-5.html\">Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[765,131],"tags":[129],"class_list":["post-10813","post","type-post","status-publish","format-standard","hentry","category-85426-79-5","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-01T19:24:18+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813\",\"name\":\"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-11-01T19:24:18+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10813#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives","description":"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813","og_locale":"en_US","og_type":"article","og_title":"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives","og_description":"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-11-01T19:24:18+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813","name":"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-11-01T19:24:18+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"On August 21, 2019, Lancellotti, Patrizio; Oury, Cecile; Pirotte, Bernard published a patent.Safety of 4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine The title of the patent was Preparation of pyrimidine derivatives for use as antibacterial agents. And the patent contained the following:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=10813"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10813#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Lancellotti, Patrizio et al. published their patent in 2019 |CAS: 85426-79-5"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10813","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10813"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10813\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10813"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10813"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10813"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}