{"id":10770,"date":"2022-10-28T06:39:16","date_gmt":"2022-10-27T22:39:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10770"},"modified":"2022-10-28T06:39:16","modified_gmt":"2022-10-27T22:39:16","slug":"zakharov-v-v-team-published-research-in-russian-journal-of-physical-chemistry-b-in-2019-2075-46-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10770","title":{"rendered":"Zakharov, V. V. team published research in Russian Journal of Physical Chemistry B in 2019 | 2075-46-9"},"content":{"rendered":"

Pyrazoles are synthesized by the reaction of \u03b1,\u03b2-unsaturated aldehydes with hydrazine and subsequent dehydrogenation. 2075-46-9, formula is C3H3N3O2, Name is 4-Nitro-1H-pyrazole. Substituted pyrazoles are prepared by condensation of 1,3-diketones with hydrazine (Knorr-type reactions). For example, acetylacetone and hydrazine gives 3,5-dimethylpyrazole. Synthetic Route of 2075-46-9<\/a>.<\/p>\n

Zakharov, V. V.;Chukanov, N. V.;Zyuzin, I. N.;Nedel’ko, V. V.;Korsunskii, B. L. research published \u300a Thermal Decomposition of N-[2,2-Bis(methoxy-NNO-azoxy)ethyl]-4-Nitropyrazole\u300b, the research content is summarized as follows. The thermal decomposition of high-energy N-[2,2-bis(methoxy-NNO-azoxy)ethyl]-4-nitropyrazole is studied and the composition of the products formed is determined using differential scanning calorimetry, thermogravimetry, mass spectrometry, and IR spectroscopy. Its heat of melting, as well as the heat and energy of activation and the preexponential factor for its thermal decomposition, have been determined The mechanism of the process is discussed. It is shown that introducing a nitropyrazole fragment into a diazene oxide mol. does not lead to a decrease in its thermal stability.<\/p>\n

Synthetic Route of 2075-46-9<\/a>, 4-Nitro-1H-pyrazole, also known as 4-Nitropyrazole, is a useful research compound. Its molecular formula is C3H3N3O2 and its molecular weight is 113.08 g\/mol. The purity is usually 95%.<\/p>\n

4-Nitropyrazole, is a building block for the synthesis of various pharmaceutical compounds, including inhibitors, and therapeutic agents. It can be used for the synthesis of highly selective, brain-penetrant aminopyrazole LRRK2 Inhibitor, as a potentially viable treatment for Parkinson’s disease., 2075-46-9.<\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Synthetic Route of 2075-46-9<\/a>, 4-Nitro-1H-pyrazole, also known as 4-Nitropyrazole, is a useful research compound. Its molecular formula is C3H3N3O2 and its molecular weight is 113.08 g\/mol. The purity is usually 95%.<\/p>\n

4-Nitropyrazole, is a building block for the synthesis of various pharmaceutical compounds, including inhibitors, and therapeutic agents. It can be used for the synthesis of highly selective, brain-penetrant aminopyrazole LRRK2 Inhibitor, as a potentially viable treatment for Parkinson’s disease., 2075-46-9.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[152,131],"tags":[732],"class_list":["post-10770","post","type-post","status-publish","format-standard","hentry","category-2075-46-9","category-pyrazoles-derivatives","tag-m-w100-150"],"yoast_head":"\nZakharov, V. 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