{"id":1072,"date":"2020-11-20T10:28:41","date_gmt":"2020-11-20T02:28:41","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1072"},"modified":"2020-11-20T10:28:41","modified_gmt":"2020-11-20T02:28:41","slug":"some-scientific-research-about-1456-tetrahydrocyclopentacpyrazole-3-carboxylic-acid","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1072","title":{"rendered":"Some scientific research about 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid"},"content":{"rendered":"

5932-32-1<\/a>, A common compound: 5932-32-1, name is 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.<\/p>\n

To a mixture of 1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid (A-3) (2.50 g, 16.43 mmol) in DMF (16.43 ml) at ambient temperature were added TEA (2.75 ml, 19.72 mmol), HATU (7.50 g, 19.72 mmol), and (2R,6S)-2,6-dimethylmorpholine (2.84 g, 24.65 mmol). The mixture stirred for 3 h before acidifying with AcOH (5 mL). The mixture was purified directly by column chromatography on C18 column (5-95% ACN\/water with 0.05% TFA modifier) to afford the title compound. MS: 250.3 (M+1).<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[202,131],"tags":[126],"class_list":["post-1072","post","type-post","status-publish","format-standard","hentry","category-5932-32-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSome scientific research about 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid<\/title>\n<meta name=\"description\" content=\"5932-32-1, A common compound: 5932-32-1, name is 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1072\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Some scientific research about 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid\" \/>\n<meta property=\"og:description\" content=\"5932-32-1, A common compound: 5932-32-1, name is 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Some scientific research about 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid","description":"5932-32-1, A common compound: 5932-32-1, name is 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. 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